Kimble makes the mistake of going to Clark City, a corrupt gambling town. Fred Johnson (the one-armed man) is there as well, and has two corrupt cops beat up Kimble. When Richard survives the attack, Johnson then puts out a contract on him. Kimble eventually catches up with Johnson, beats the garbage out of him, and tries to turn him over to the police-who are working for a local mob figure. The small-town syndicate has to decide what to do with both troublemakers: dispose of them, or let them go?

While working as a veterinarian assistant in a rural town in Utah, Kimble becomes aquainted with Ruth Simmons, an unwed teenage mother whom has a sickly infant. But her father, Joshua, is a Christian Scientist whose religion prohibits the use of medicine for any ailment. Kimble brings over antibiotics, but Joshua destroys the drugs. After determing that the baby is anemic, Kimble secretly arranges for a blood transfusion. Meanwhile, after stumbling upon Kimble's true idenity, a would-be deputy, named Pete, searches for the fugivtive with the aid of his two bloodhound dogs.

While working in a film supply store as a photo developer, Kimble spots Fred Johnson, the one-armed man, in a photo. After tracking down the freelance photographer, Howie Keever, whom took the photo, Kimble learns that Johnson works at a nearby chemical warehouse. Kimble goes to the warehouse and suprises Johnson. During the scuffle, Johnson accidently ignites some chemicals, chreating an expostion which leaves him badly injured and Kimble blinded by the flash. Johnson manages to escape and once again reports Kimble to the police. Kimble manages to escape from the hospital before the police arrive and tries to get back to Howie's apartment to ask him to hide him. But the police question Howie and his uncle whom learn Kimble's true idenity, as well as the $10,000 reward.

Carl Crandall is the wealthy and spoiled son of winery owner Pete Crandall. Carl stops a labor strike at the winery by killing the union leader and framing Morales, another worker, for it. Kimble happens by and witness Carl run from the scene of the crime, but he is unable to tell anyone because of his secret. Kimble tries to write an annoymous letter to the California District Attorney, but Carl's goons confiscate the letter. While Kimble tries to persuade Morales's wife, Elena, to help him report Carl to clear her husband, Pete suspects Carl of the murder and sends his two right hand men to keep an eye on Carl. But the two men are in league with Carl who orders them to murder Kimble.

After Kimble spots Fred Johnson at the scene of a fire, he gives chase-but stops to help a woman who has been hit by a vehicle. After Kimble helps her get to a hospital, he discovers that she is Johnson's girlfriend. Meanwhile, Johnson has contacted her and told her to contact the police. Eventually, Gerard arrives at the hospital, as a result of a tipoff, and tries to lay a trap for Kimble.

While fleeing from a sheriff's dragnet, Kimble is rescued by a dangerous motorcycle gang called 'the Devil's Disciples, led by the brutal Hutch. As payback, Hutch and his gang want Kimble to help them avenge the death of a former gang member who robbed a gas filling station, where his father turned him in and as part of his sentence; he was drafted and sent to Vietnam where he was killed in action. When Kimble notices that the gang is not completly unified, he seeks help from Don, one of the members, and his girlfriend, Patty, to help him escape so he can warn the police to prevent the killing of the deseased gang member's father.

While hopping a freight train, Kimble meets a wounded criminal who demands to take him to a rendezvous point in the hills of Southern California. Kimble reluctantly does which is an isolated cabin in the deep woods where they are joined by three more men whom happen to be robbers of an armored car who demand from the criminal their loot. Not believing their accomplice's true story that he lost the money when it fell off the train due to his gunshot injury, the three robbers hold Kimble, a widow named Laura Craig, as well as a park ranger who happens by, while torturing the man for the location of the money.

While working as a clerk in a small grocery store in Ocean Grove, California, Kimble becomes embroiled in a conflict between his co-worker Larry Corby and his father Ben, who's the town sheriff. When Ben refuses to support Larry and his pregnant girlfriend, the boy dons a mask and robs the store. After being shot during the escape, Larry drives off while Ben gives chase. Larry runs off the road and Ben is shocked to find his son as the holdup man. Ben then hides Larry and after recognizing Kimble, makes a bargain: if Kimble can save his son's life, Ben will set him free.