On an island near Greece, UNCLE Agent, Mark Slate watches as a Thrush agent tests a new drug by spraying it on some partying villagers. The drug slows them to half speed. If the drug is unleashed on the world, ecomonic chaos would ensue. The only known antidote is on its way to the Island via commercial flight ... on the fleas of a dachsund accompanied by UNCLE Agent, April Dancer.

Professor Quantum has created a seemingly useless machine that extracts the color out of everything in it's wake. A stranger, however, offers the Professor anything he wants in exchange for the Light Variator. April, posing as a lab assistant, has been sent to keep an eye on Quantum and he has fallen in love with her. The professor decides that what he really wants is his ""lab assistant"" and he's willing to turn over the machine if his wish is granted.

A crime syndicate learns that it is being investigated by April. The boss, Dossetti, orders her killed but one of his men finds her appealing and kidnaps her to be part of his harem. The syndicate intends to create a diversion with a UFO and to raid the Royal Palace.

UNCLE has received information on an attack by Dr. Vladimir Toulouse. He has created a pill that gives superhuman strength to anyone who takes it and has threatened to unleash a superhuman army unless a ransome is paid.

Thrush Agent Mother Magda is plotting the elimination of world leaders and planning to replace them with exact doubles. Mark loses the tape with all the details as to how it will be done. April and Mark must recover it immediately.

The Utter Anguish Gold Mine is up for grabs when the owner dies. The mine contains a huge vein of Triterian crystals that can be used to make death beams from laser light. Thrush and UNCLE are VERY interested in acquiring the mine.

A retired gangster from Chicago is second in line to rule a small Mediterranean country. He assassinates the Duke leaving only one person in his way, Major Stella who is currently saving souls in London. Mark and April are sent to persuade her to save her country.

A former classmate of Waverly's owns a bodyguard service. When one of the clients is murder, only the body guards are present but they don't recall it happening. Waverly sends April and Mark investigate.