Dr Sam Morgan arrives in Cardale as David's locum. He is thrown straight into the deep end when he has to tell a pregnant patient she has cervical cancer. Joanna has dinner with old flame Martin Henderson and gets a lot more then she bargained for when it is clear he is still in love with her. Meanwhile the romantic tension between Andrew and Dawn is brought to the fore.

After disaster strikes at their home, Dawn and her children move in with Andrew. But as relations between Andrew and the children are frosty, family bliss looks unlikely. Alice struggles to come to terms with memories of her attack and Joanna and Martin reach an understanding over their relationship.

Andrew and Dawn face a tough time when Trent becomes seriously ill, however the arrival of Trent's dad Keith signals that their problems have only just begun. Elsewhere Alice returns home and Sam takes part in the community tug of war.

Back from their holiday but not rid of their problems, Andrew and Dawn return to Cardale and have some uncomfortable questions to answer about their relationship. Elsewhere an old friend causes problems for Sam.

The end looks nigh for Andrew and Dawn when Keith's presence cracks their already fragile relationship. Will Andrew lose Dawn to a man she feels little for. Meanwhile Alice, Joanna, Sam and Kelly rally around Rita when she has a fall.

A meningitis outbreak throws Cardale into chaos. Andrew, Erica and David work around the clock trying to avoid further cases of the disease and convince the health authority that all the children need to be vaccinated. Meanwhile Andrew and Erica discuss their relationship

Dawn's outlook on life is suddenly changed when she finds a lump on her breast. Terrified she will die from the same disease that killed her mother; Dawn refuses to have any medical treatment. It's down to Erica to try and convince her to seek medical help, but it will it be Dawn's children who give her the real incentive to live?

Cardale prepares for the wedding of Andrew and Erica but a long line of disasters provides them with the perfect pre wedding initiation test. The pop band turns into a group of line dancers, the caterers pull out and the grooms suit doesn't fit, but surely the most pressing issue is the last minute doubts looming over the bride.......

Joanna and Martin take on the sensitive case of a terminally ill teenager. Andrew and Sam go out of their way to help a couple stranded on a riverbank but things take a turn for the worse when Andrew is badly injured. Unconscious and unresponsive - is this the end for Andrew?

Joanna and Sam plead with hospital medics and ask them not to give up on trying to revive Andrew. Dawn keeps an anxious vigil by his bedside whilst Keith returns demanding to look after the children. Elsewhere Martin's vulnerability is shown after his high profile case ends in the worse possible way.

Andrew finally comes face to face with Keith after Dawn decides to leave Cardale - will he let her walk away? Sam is knocked sideways when Anna returns - does her future lie with him? It's new beginnings all round as Andrew, Joanna and Sam face the future without their partners.