Grissom and Warrick get the case of an old woman found mummified in her closet. Sarah and Nick arrive to investigate a breaking and entering to find a raped teen. These cases are not as disparate as they first seem. Catherine looks into a gun found by a boy. The gun is connected to a week old murder across town that Warrick caught.

When a has-been boxer is killed, the CSIs must establish which of several life-threatening acts actually killed him.