Grissom and his team investigate the starving death of a five year old boy. They discover the boy has siblings who are in danger too. Catherine and her team determine who killed a prisoner in a holding cell brawl.

Grissom, Sara, and Nick investigate a wildfire that killed one man and badly burned a woman. Catherine, Nick, and Warrick get the case of a family of three murdered in their home.

The team investigates the death of a psychic who "saw" her own death while performing a reading for two other women. Greg reveals a family secret to Grissom but Grissom believes that science will be what solves the case.

A man accused of murdering his wife and co-workers leads the CSIs on a wild ride through a busy casino, eventually barricading himself and a hostage in a casino hotel room. The CSIs process the evidence from the crime scene to determine whether or not the man acted alone or had an accomplice. One of the CSIs eventually steps in as a hostage negotiator, putting himself in danger.

Langston and Riley are taken hostage during the aftermath of a shootout in an usually calm Las Vegas community.

A rising young star is killed in a wreck and her determined stalker claims credit, but the team finds out there's more to this tragedy than meets the eye.