Brennan and Zach investigate a small jet crash that was carrying some Chinese diplomats and a woman. At the crash site, Brennan finds some bone fragments that do not belong to any of the passengers, but might belong to a man who has been missing for five years. Although ordered to work only on the diplomats, Brennan and her team go rogue to try to discover the identity of the extra bones.

A train carrying a popular Senator is derailed by a car positioned on the tracks. Brennan works out why the dead body of a rich businessman was placed in the car, and the search continues for her father. The team has a new boss.

While investigating the death of a film student who was working on a documentary about the legend of a headless witch, who haunted woods in the 1700's, Brennan develops a strong bond with the victim's brother.

The team investigate the death of an Asian woman found without any bones left in her body.

When Angela draws the face of an old woman to go with the decomposed skeleton of someone much younger, they soon learn the victim had Progeria, an aging disease. Booth and Brennan investigate to discover who would want to kill such a fragile person. Meanwhile, Hodgins and Angela's walk down the aisle doesn't go as planned.