Captain Kirk must find the cure to a deadly disease and put an end to another Starfleet captain's cultural interference.

An alien female beams aboard the ship and, after incapacitating the rest of the crew, surgically removes Spock's brain. Kirk and the crew have just hours to locate and replace it before Spock's body dies.

An alien device on a primitive planet erases Captain Kirk's memory, and he begins a new life with the planet's indigenous people.

Captain Kirk is caught between dimensions while the crew of the Enterprise works to retrieve him. All the while, the Tholians demand that the Enterprise leave their space.

Invisible "time-accelerated" aliens take over the Enterprise and attempt to abduct the crew for use as "genetic stock".

Captain Kirk faces off with a demented shape-shifting starship captain determined to control the universe.

Captain Kirk races against time to acquire plague-fighting minerals from a world in the midst of a civil uprising against a grievous social class disparity.

Aliens force Captain Kirk and First Officer Spock to join forces with "Abraham Lincoln" and "Surak" to battle villains in a contest of good vs. evil.