The scourge of polio invades the Metcalf-Kahn home as new mother Anne is stricken with the disease, her family is quarantined and others who come in contact with her fear the worst. Meanwhile, Mike dreads the coming of another birthday; and 50-year-old Abe fears he's losing his memory, just as his father did.

TV seems to be the wave of the future, which could signal the end of Ginger and Jeff's radio show; a local sportswriter receives kudos after Judy ghostwrites his column on the Indians; and suspicions of infidelity lurk at the Sloan home.