Amos and William Cole come to Dodge to find the backshooting killer of their outlaw father many years before.

Kitty saves the life of a man during a stage hold-up, taking him back to his ranch she finds his mother a ruthless matron and his daughter alienated from her father.

Grant Lyle, a former lawman with crippled hands, brings his young gunfighter son to Dodge to settle the score with Hoxey, the man just released from prison who is responsible for his hands.

Festus is rescued from a rock avalanche by a young hide cutter. His fellow cutters are following a herd of cattle with hopes of stealing them for the hides.

A comedic episode. Two hillbillies attempt to turn their 102 year-old relative in for the bounty on him.

Con man, Bob Sullivan tries to trick a widow with three children out of money for a fake cattle herd, but instead ends up falling in love with her and her children.

Mountain man Luke Brazo joins Matt in a hunt for a vicious wolf terrorizing the area.

Doc is given the choice of saving the life of a man he saw commit a murder and delivering a baby. He choses to save the man first, and the baby dies in childbirth. The baby's father, Tom Butler blames Doc and plans to get even.

Matt is taking a signed confession paper to a Judge that will hang a man, the man has put a reward on the paper causing two bounty hunters to shoot Matt in an effort to get it. Meanwhile, Matt is taken in by a group of freed slaves heading West, and now being pursued by the hunters.

Matt is summoned to Coreyville, a run-down cowtown, by a young woman whose brother is on trial for murder.

An old friend of Kitty's learns he is dying comes to Dodge to try to ""go out in style"".

In an attempt to help his blind daughter, farmer Ben Hurley steals horses for an outlaw gang. Deputy Newly O'Brien arrives at his farm investigating, followed by the outlaws.

Sergeant Holly, a alcoholic loving veteran is getting ready to retire. Just hours before it, a Apache prisoner in his custody escapes with Kitty as a hostage, forcing the Sergeant to go AWOL to get the prisoner back.

Doc Adams's old friend is thought to be a thief.

Matt must rescue a teenage girl from indians and bring her back to her family.

With Matt out helping the Army deliver a gold shipment, Dodge is wide open for Morgan and his men to come in with a Gatlin gun and take over. Breaking into the Long Branch, Morgan is helping himself to whiskey when Kitty shoots him hitting him in the shoulder and the face. With Matt and the gold on the way and Morgan sitting with a big gun and a fever and a crazy streak from the permanent scar he's gonna have, Dodge can only wait to see what comes next.

After an outlaw becomes a victim of his own gang he tries to Matt bring in the gang that made him a victim.

Doc Adams feels that Sam McTavish (who is a woman Doctor) may replace him.

A wounded outlaw comes to Dodge City to find his daughter before his death.

After a yong man kills a gunfighter he become the victim of publicity.

In order for a black man to save his life he must say that indians held up a wagon train.

Matt has two problems he tries to arrest an outlaw then he must try to free the hostage.

Sgt Holly has stolen an army payroll and is framed for it.

Festus becomes a rich man.

A convict returns to Dodge City to get a woman back.

Sally Fergus, called by many in Dodge ""Dirty Sally"" finds young wounded outlaw, Cyrus Pike at her home and nurses him back to health. His partners in a robbery are searching for him and their stolen loot.

Dirty Sally becomes smitten with the outlaw Pike as he continues to heal up and the gang begins tracking Pike down.The friendship between the two grows as Pike is faced with leaving or standing his ground with the gang.

Matt is out to find a gunfigther who killed two people.

A hidecutter starts trouble in the Long Branch and Matt comes to the rescue throwing him out of town. When Festus goes up to fetch Dr. Chapman, he finds the old scudder there himself. Offering to buy Doc a drink, he can't resist and they surprise everyone down at the Long Branch. While they are all excited to see Doc, Matt is out checking the town and ends up shot in the back by the hidecutter he just threw out. Doc's homecoming is ruined when he realizes that if he tries to remove the bullet he could paralyze Matt and he doesn't want to be the one to do it. So, he contacts a surgeon in Denver, and loading Matt in the baggage car of the train, Kitty, Doc, Festus, and Newly all head for Denver along with a Federal gold shipment.

As the train moves along to Denver we meet several passengers. One is a Pinkerton man handcuffed to Beth Tilton, a woman who doesn't want to go back to Colorado to her husband. The other, Allie Dawson, is a young girl that Newly befriends who does not believe in violence. The train is taken over by Jack Sinclair, an old enemy of Matt's. Matt had shot his hand off before sending him to prison. Making it look like Matt is a dead body in the baggage car, he is safe for now with Doc standing guard, but it can't last long. Kitty senses trouble when Beth starts cozying up to Jack Sinclair and worries she'll tell him what she knows. Warning her that she'll do anything for her man, Kitty watches Beth like a hawk. Festus and Newly are forced to help load the gold shipment on the wagon and when they get it loaded they end up driving off with it luring the gang out on foot to chase them. Beth tells one of the guards about Dillon in the back, and he goes to kill him.

The conclusion to this three parter. Dillon kills the guard that was gunning for him and the passengers take the train back over. The only problem, all the fuel has been destroyed so they have to get more fast. Festus and Newly are still out with the gold leading the men from the train on foot. Dillon's legs are numb and Doc has no choice but to operate whether he cripples him or not. Leaving the gold shipment and taking the mules, Newly and Festus head back to the train to try to get it going. Sinclair has the men push the wagon back to the train and gets there in time to keep it from taking off. Beth tells Sinclair about Matt Dillon, but Dillon's faster than a gun even lying down and ends up killing him. The train takes off leaving the bad guys and all their gold sitting at the tracks with no way to get anywhere.

Newly falls in love with a woman who could put him in danger, once her past is known.

Lucius's daughter wants her dad locked up so she and Tom can have the estate. Judge Broker thinks Mr. Prince is sane and Mr. Prince proves he can be a dad.

A former gunfighter returns to Dodge which worries Matt because Howard Cane was the one to survive the rage war. Can Matt stop him before more trouble comes to Dodge?

A father disapproves of the man her daughter marries.

Daniel Shay comes to Dodge City as a drummer who peddles rat traps as a way of making money. While Daniel continues to look for buyers of his rat traps, he sees a Cheyenne boy stealing a horse. As he looks on memories of a battle at Rock Creek return.

While having dinner with Sarah Morgan Mr. Shay wonders about Jimmy Morgan's father who died in the Rock Creek massacre, Sarah mentions that the cavalry ran him down.

When a family man lawfully kills a murderous outlaw by shooting him in the back, some people in town start to physically abuse him.

Festus runs into Jesse Dillard who is wanted for shooting a black man. Festus wants to find out more and take his friend to prison.

Ron Moody guest stars as a man torn between keeping his own self-respect and the friendship of a young boy or keeping his drunken promise to help two hired gunmen.

A gunfighter wants to forget his past... and wants everyone else to forget it too. Unfortunately for him, this is not easy to accomplish...

James Stacy stars as a roguish thief who's long on charm but a bit short on ethics. His real test of character comes on a long, adversity-plagued journey to Dodge with his captor Festus.

Dillon forces an alcoholic Circuit Judge to hold an inquest into the death of a woman saloon owner which had resulted in the lynching of an innocent drifter.

Nellie and Susan get ready to leave for St. Louis when Matt brings a prisoner to be treated for a wound he got while robing a bank. Susan wants to leave for St. Louis right away. Susan worries she and Nellie may never leave because of her love for the prisoner.

Mr. Boswell asks Nellie to marry him. Susan puts a stop to Nellie getting married.

Billy comes back to Dodge because he has trouble finding anyone to listen to his stories and visit Festus who is a friend of his. Billy retarded and tells Festus a riddle and the answer given isn't funny to Billy, Doc tells Festus that Billy has the mind of a seven or eight year old and needs better care.

Billy sees a man hurting a cat and almost kills the man, not knowing that what he did was wrong Matt and Festus talk to Judge Brooker and Festus becomes a guardian to Billy. When a deer is shot for food Billy attacks Festus. Festus has a hard time trying to make Billy understand why the deer was shot.

Doc tells Festus to take Billy back to where he came from but finds that hard to do. They go to the place Doc suggested and Billy gets worried about the noises inside the place. Festus tells Billy he is going to kill rabbits for dinner and try to give Billy a taste of life.

Matt, Doc & Festus find Billy telling kids stories at an orphan's home.

After being forced to shoot a man who is breaking up the Long Branch, Matt goes off to be alone only to find a young girl and a newborn in a cave. Neither she nor her parents want the child, and they send it with Matt. Matt finds the only logical choice, Miss Kitty, to deposit the baby with till something can be done with it. Matt decides to give it to the widow of the man he just killed but doesn't realize that Kitty is willing to sell the Long Branch to keep the baby for herself.

Sarah takes her class on picnic trip to enjoy nature but is attacked by Mr. Stokes who is drunk and will have a baby but doesn't know yet and has hidden the secret. Doc tells her but she doesn't believe him. Mr. Pruitt and his son Lester love her.

Carl feels hurt that he couldn't tell Sarah he would love the baby anyway. Carl goes to jail for not telling Matt why he fought Mr. Stokes. Sarah doesn't want to help Carl get out of jail because she was attacked and wants to leave Dodge.

Buck Henry Woolf is on the trail of his uncle, who killed his father, stole their money, and wounded him. Festus is on the same mission and also to stop the young man from taking the law into his own hands.

A group of bandits attempt to rob a town while masquerading as soldiers.

Matt houses a drunk Will & Friends in the jail they go looking for $300 that they think Bill took. Matt thinks it was a misunderstanding. Will doesn't want to tell Matt that they shot Curly Wills (They buried him before going to Dodge.

Doak stops to see his girlfriend and says marriage will need to wait, as Will & Quincy leaves without Doak Quincy and the storekeepers are shot.

A series of seemingly random killings have the citizens of Dodge City in near panic, but Dillon believes they are part of a pattern in which Doc is slated to be the next target.

Lee J. Cobb and his daughter Julie Cobb appear together for the first time when Cobb guest-stars as a once-proud military officer who is suddenly faced with a painful and unplanned reunion with his daughter.

Matt takes a young orphan Bessie Sutherland after her parents were killed on the prairie, to live with her Aunt Rachel. Rachel tells Matt that because of the devastating experiences that she has had, does not want to take in her niece, besides she wants to sell her land.

Matt Dillon is sentenced to life imprisonment of hard labor for shooting a fugitive in the town of Bedrock.

Two bronco busters try to raise money for a ranch in Montana, only to have the dream ruined when one of them gets a death threatening head injury when thrown off by a wild stallion.