Luffy faces against Urashima in a sumo match. Holdem tries to pull off Tama's cheek until Luffy sends Urashima crashing into Holdem's residence.

Kin'emon explained to Luffy's group, who just arrived, the preparation they have done till now and assigned new tasks to them. He laid out the plan of how they are going to defeat Kaido, but there are still lots of work to do such as recruiting more allies and gathering more information on the enemy.

Luffy continues his furious battle with Kaido. Despite his best efforts, the battle ends in Luffy's defeat.

Zoro goes to a gambling house with Tonoyasu. After a brawl, they go to Ebisu Town. Meanwhile, the Ninja-Pirate-Mink-Samurai Alliance works to steal weapons and food. Franky learns that Minatomo no longer has the blueprints of Kaido's mansion. He goes all over the Flower Capital searching for them but hits a dead end. At the shogun's castle, CP-0 attempts to negotiate with Orochi.

Nami, Robin, and the others got away from Oden’s Castle and now discuss what they have found out about the enemy so far. Meanwhile, Chopper’s group sets off to rescue Luffy from the Excavation Labor Camp where, at the same time, Luffy is in big trouble.

Luffy’s next enemies in the deadly sumo match in the Excavation Labor Camp are two tough Gifters. Much to Old Man Hyo’s surprise, Luffy keeps practicing using Haki properly at the same time as he fights them. Meanwhile, the wounded Zoro wakes up to find out the stunning identity of the mysterious woman he saved.

As the citizens of Ebisu Town grieve over Yasuie's death, Shinobu reveals more information about the SMILE fruits. Toko enters the execution site, hoping to revive her father. Seeing Toko, Orochi attempts to kill her as well, but Zoro and Sanji step in and save her.

Right after Big Mom regains her memories, she suddenly faints. Queen quickly orders his men to restrain Big Mom and escorts her to Onigashima. With both Queen and Big Mom away, Luffy continues practicing with advanced Busoshoku Haki. Babanuki then orders the prisoners to subdue Luffy, and they comply. Daifugo also fires toxic bullets on the prisoners. Before Luffy could be infected, a mysterious prisoner shouts out.

The Mountain God continues its rampage in the Flower Capital until Oden confronts and defeats it. After this incident, Oden was expelled from the capital. Due to their admiration for Oden, Kin'emon and Denjiro decide to follow him.

Oden and the Roger Pirates head for the Land of Wano to obtain a copy of the Road Ponegliff. Oden sees Kin’emon and the others for the first time in years, but he immediately returns to the sea leaving his wife and children behind. Then, after stopping by at the Mokomo Dukedom and getting a copy of the last Road Ponegliff, the Roger Pirates finally make it to the last island.

As Kin’emon and the others run to Oden Castle to save Oden’s family, the castle is set on fire and Kaido attacks Toki and her children. Leaving Momonosuke to Kin’emon and Hiyori to Kawamatsu, Toki appears in front of the desperate people of the Land of Wano and gives a prophecy.

To Law and the others’ surprise, Luffy and the rest of the Straw Hats attack the giant torii gate in front of Onigashima. Meanwhile, Kaido and Orochi are having a big banquet on the island where Kaido’s formidable subordinates, the Tobi Roppo, are called in.

The furious Big Mom chases Brachio Tank driven by Chopper and Usopp, but they bravely fight back! Meanwhile, Kanjuro takes the battered and bruised Momonosuke to Kaido and Orochi, then breaks the news to them about Oden’s retainers who were thought to be dead.

The Akazaya members deliver a crushing blow to Kaido. Luffy and Yamato try to back them up, but Ulti stands in their way and Big Mom spots Luffy. Meanwhile, Nami and Carrot free themselves from their enemies and move on to take back Zeus!

Drake vows to fight alongside Luffy, but Zoro becomes skeptical and challenges him to a fight. Meanwhile, Usopp’s practical joke pushes Nami into confronting Ulti, who is infuriated since her brother got attacked.

Carrot and Wanda step in to help Marco, who is cornered by Big Mom and Perospero. In the meantime, Yamato fights a fierce battle against the Animal Kingdom Pirates Armored Division led by Sasaki, while protecting Shinobu and Momonosuke.

Yamato tells Momonosuke and Shinobu about how Ace gave him hope for the future. Meanwhile, Luffy and the other allied pirates from the Worst Generation make it to the rooftop to finally face off against Kaido and Big Mom.

Chopper works hard to make the cure for Ice Oni, even though he is turning into one himself. Meanwhile, the infected Boss Hyogoro the Flower regains his youth and fights fiercely to protect Chopper and the others.

Luffy and Uta run across Windmill Village, compete with each other, and share their dreams with each other. They also pledge to build a new genesis for everyone to live happily. However, one day, the unexpected happens.

Luffy and Kaido who have both infused themselves with the Color of the Supreme King clash! Meanwhile, Nami, Usopp, and Tama are running from Page One to get to the Performance Floor, but they bump into another tough enemy, Big Mom.

Nami strikes a thunder blast to clear the way to the stage on the Performance Floor. However, the elite corps of the Gifters shows up to crush their inferior opponents. Upset but unbroken, Otama stands up to give a command!

Momonosuke faces Kaido once again trembling in fear. However, with Luffy’s encouragement, he bravely steps up and shows his dragon fangs remembering what he had to go through because of Kaido.

Sanji is tormented by the idea of becoming a cruel Germa warrior like his siblings and torn between being strong or being humane as he is now. When he makes up his mind, he asks Zoro the ultimate favor.

In the Flower Capital, the Fire Festival is about to end. On Onigashima, the battle between Luffy and Kaido is getting even more intense. However, Kaido who is excited about having a strong opponent starts drinking too much.

The battle between Luffy and Kaido comes to an unexpected end. Kaido comes down and tells everyone that Luffy has been defeated and the Land of Wano is finished. Momonosuke and Yamato argue over whether they should still continue fighting.

The samurai and the Straw Hats shout for joy as they hear that Luffy defeated Kaido. Meanwhile, Momonosuke informs Zunesha of a major decision that he made. However, when Yamato calls on the Animal Kingdom Pirates to stop fighting, the earth trembles.

Angered by Luffy's attempt to leave without saying goodbye, Momonosuke rushes with Kin’emon and Yamato to the port from where the Straw Hats are about to leave, thinking back on his days with Luffy.

While Luffy and the others are enjoying the futuristic machines of Egghead, someone who resembles Bartholomew Kuma comes after them. When Luffy tries to fight back, Bonney stops him and reveals her shocking relationship with Kuma.

CP-0 led by Rob Lucci makes a forced landing at Egghead and people on the Fabriophase are plunged into confusion while Shaka and the others prepare to fight back on the Labophase. The enraged Atlas stands up to defend the peace of the island.

CP-0 takes control of the Fabriophase but gets attacked by an unknown force. Meanwhile, in the Labophase, the Straw Hats and Dr. Vegapunk’s Satellites find out that Vegapunk has disappeared and begin searching for him.