The Straw Hats without Luffy, Chopper, and Jimbei are taken to the laboratory on the clouds far above the ground by Lilith. They get excited about the things they've never seen before. However, inside the laboratory, a new threat is waiting for them.

Luffy transforms into the Warrior of Liberation as Rob Lucci also shows his awakened Devil Fruit form. As the two clash, Vegapunk reveals the shocking truth of the Gum-Gum Fruit and his eye-opening theory on Devil Fruits.

CP-0 enters the Labophase and starts attacking the Thousand Sunny as soon as they find it. Luffy reunites with Nami and the others but finds out that Vegapunk is missing. Meanwhile, Bonney is pressing Vegapunk to change back her father Kuma.