Sid and Buntz wrestle with 80 lbs. of cocaine found in a suitcase at the site of a small plane crash; Goldblume looks into a suspected case of aspirin tampering; Belker goes under to look into a hotel owner scamming city housing chits from vagrants; Hill and Renko handle a domestic call concerning a woman abusing her invalid grandparents.

Buntz is in charge of efforts to protect a convicted mobster on his way to jail from a killer hired by his nephew; Russo's undercover places her in another sexually fraught position; LaRue and Washington bust a guy who confesses to several unsolved murders; Jablonski helps Belker bust a bus bandit; and Calletano resigns from the force.

Sid and Furillo work to find out who is setting up Buntz while Daniels publicly vilifies him; LaRue decides to beat a TV crew doing a live broadcast from a gangster's cellar to the punch; Bates agrees to go out with Sal the plumber; rumors are flying about what will happen to the station house after a three-alarm fire guts it.