Nobody takes much notice when a death row inmate vows on the electric chair to come back from the dead and kill five men who have wronged him during his time in prison, until a guard is mysteriously murdered in the former inmate's cell.

Mulder seeks the help of a woman who he believes has a special connection with a young girl who has recently been kidnapped by the same man who held her captive many years earlier.

Mulder and Scully swap roles as they pursue a man killing priests that claim to have the wounds of Christ. The agents find and must protect a young boy who may be a real stigmatic. While Scully's faith draws her close to the boy, Mulder is convinced of another explanation.

A serial killer is captured after a three year manhunt, and he claims an evil spirit is responsible for the crimes. When the killings continue as he sits in jail, Mulder's battle with a former colleague gets more heated when he suggests that something more paranormal may be involved.

Mulder and Scully are asked to help in a case involving Robert Patrick Modell, a murderer possessing the psychic ability to force his will onto people. Due to a brain tumor that is slowly killing him, he is searching for a "worthy adversary" and forces Mulder into a battle of mind over matter.