Carla Chaney is caught seemingly red-handed at the scene of the murder of her ex-boyfriend. Perry agrees to take the case pro bono after three other attorneys drop out. Carla's only hope is an unseen woman she claims was also present at the scene. According to Carla, this woman had a sinister laugh.

The Safeline Insurance Company notices an increase in heart attacks among their policy holders. The company suspects fraud and hires Perry and Paul to investigate. When Paul goes undercover as a construction worker, he almost doesn't survive the assignment.

Tryon Laboratories hires the Drake Detective Agency to protect their latest formulas. In spite of Paul's best efforts, there is a leak in security and some top-secret information is stolen. One night, Leigh, an undercover agent working for Dr. Scranton, the head of the company, calls to say he knows the identity of the spy. Scranton and Paul rush to the laboratory only to find Leigh dead, floating in a vat of water.

Victor Montalvo, co-owner of the Golden Bear Club, gives a ride to a sweet young thing named Debbie Conrad who later attempts to blackmail him by threatening to claim he took advantage of her. Debbie is working the scam with her boyfriend, Rick Durbin, and Montalvo decides to pay them off. But before he can make the payment his partner in the club is murdered.

Dr. Stacey Fielding takes off for Salt Lake City on business. When his plane crashes, Veronal poisioning is found in the body. Miriam Fielding is arrested since the last thing the good doctor drank was whiskey from a flash she had given him. Upon further investigation, Miriam is cleared when it's discovered that the man who really perished in the crash was Al Dolby, the plane mechanic. But where is Dr. Fielding and who did the poisoning?

An art dealer and his girlfriend are arrested for a two murders related to a series of hijacks. Paul goes undercover to ferret out the hijacking ring and Perry finds himself staring face down the barrel of a gun pointed by a killer even he never considered.

Perry plays Mr. Brownlow to young Lenny Beale who's involved with a gang of teenage car strippers. Lenny wants to quit the gang but when his boss, Bill Sikes, turns up murdered the police theorize that Lenny killed him in revenge for Sikes shooting his girlfriend.

Imagine Gerard Van Ness's surprise when a long-lost tiara worth a fortune turns up in his hands. Imagine Perry and Della's surpise when the body of a jewel thief turns up in a trunk delivered to their building. Needless to say, Van Ness gets blamed for the death and it's up to Perry and company to save the day.

Things keep going from awful to good grief for poor Ethel Andrews. First she's left at the altar by her fiancé, Bruce Strickland, who also let's her take the blame for a $50,000 securities theft since her signature was on the transfer authorization. Ethel decides to leave town but nearly has an accident with a car driven by Peggy Sutton. Peggy, it seems, is on the run from a hired killer. Ethel foolishly agrees to swap identities with Peggy but then Peggy perishes in a car accident. Ethel then finds $50,000.00 in the trunk of Peggy's car and makes the mistake of informing Bruce Strickland who turns up murdered. Perry sends Paul Drake up to Lake Tahoe to find out about Peggy Sutton but it might be too late because the noose is getting pretty tight around poor Ethel's neck.

Nasty oilman Jerome Klee is shot to death and there's no shortage of suspects. Perry's client is Klee's foreman who tried to change his boss's mind about backing out on a drilling contract on a low income family's land.

Perry has all sorts of troubles in this one including a client who takes a shot at him. It starts when dim bulb prizefighter Duke Maronek gets into a fight with Art Grover over pretty model, Sharon Carmody. Duke believes he killed Grover with his bare hands. Perry discovers that a vagrant, who stole a wallet from the corpse, has been charged with the crime. He quickly gets the vagrant off the hook only to discover that Duke has disappeared. It is Sharon Carmody, the model who is up for a big assignment, who holds the keys to Duke's whereabouts and what really happened on the night Art Grover died.

A nasty actor with a lot of enemies is murdered. Perry gets his accused killer off the hook but then HE turns up dead and an aging, eccentric actress is blamed for that one. Are there two murderers on the loose or are both the work of one person?