Camille has an innocent and unavoidable mishap in the operating room during a heart transplant on the rabbi who performed her wedding ceremony to Aaron, and blames herself when the rabbi dies later, even though her mishap had nothing to do with his death; an inexperienced new nurse stands up to Arthur; wracked with guilt, Camille reveals the operating room mishap to the rabbi's widow, and only Alan's ingenuity in demanding an autopsy keeps the hospital from a major lawsuit; Aaron and Camille have it out over his lack of emotional support after the rabbi's death, and each of them admit to the hurt caused by their divorce.

Phillip is unable to save a promising young boxer who succumbs to the fatal effects of steroids his father gave him to enhance his performance in the ring; a pregnant young teenager carrying a baby with a heart defect seeks Alan's help when she is unable to find adoptive parents for her infant; Aaron fires Angela after his tax audit reveals that she's been embezzling money from his pension plan.

Kate lobbies for another heart for a prominent author whose first transplanted organ is failing and who also has a continuing heroin addiction. McNeil's gambling problem grows worse. Danny Nyland becomes a patient when he runs into a telephone pole with his car.

Dr. Kronk must decide whether or not to grant the request of a convicted child molester who wants to be castrated. Dr. Shutt struggles to regain his health after his aneurism. McNeil refuses an ""easy cure"" to a heroin addict, and Dr. Grad treats an HIV positive 14-year-old.

As Dr. Wilkes takes his son to school gunfire errupts. The victims are brought to Chicago Hope and Wilkes finds himself having to deal with his sons post-tramatic distress. Kronk also finds himself viewing the situation in a new light, due to the recent arrival of his daughter. The situation also brings back memories of his son to Dr. Watters. Catera had to operate on the shooter, and feels conflicting emotions. Dr. McNeil pops the question to Dr. Catera. Austin is still turmoiled over the incident at the cabin.

Grad accuses a mother are starving her infant to death. Shutt and Catera disagree over a neurological patient. Austin announces her plans with NASA, and Watters taked away her status as Chief of Surgery. Yeats uses his ""sixth sense"" to diagnose a patient.