Sutton's mind rells as wives two and three ask him for a very great personal and professional favor and wife one chacks in for a serious medical problem. Kate anxiously awaits news of who will be appointed as the new head of surgery. Dr. Shutt performs delicate surgery on a wealthy quadriplegic who cannot be anesthetized, and whose beautiful fiance attracts Nyland's attention.

Tommy places a bid to buy out the hospital with the intention of firing Kate as soon as the deal goes through; as Valerie continues her affair with Danny, Jack lets Danny know that he's aware of their relationship; Elizabeth is readmitted after Andy beats her again, and Andy takes his revenge when Dennis attempts to help his sister escape the cycle of spousal abuse; a mysterious biohazard accompanies a patient admitted to the E.R., and immediately begins to fell the staff; after Kate pleads the hospital's case, Jack agrees to counter Tommy's offer, but only if Phillip fires Danny; Kate and Tommy threaten to expose each other's secrets; after Diane's work for the last two years is called into question and her grant money is suspended, she decides to go to Africa to do research with a colleague; Tommy courts Aaron's support; feeling under-appreciated and ill-respected, Camille resigns; realizing that Tommy will stop at nothing to destroy her, a desperate Kate flees with their daughter an