Zack, the new kid in town, finds that even a simple trip to school becomes an adventure when he meets Milo Murphy.

After science teacher Mrs. Murawski announces a science project, Milo, Zack, and Melissa must overcome Murphy's Law to protect an egg and their grades.

Milo is allowed to attend his first school football game since the home team, The Geckos will lose anyway, but discovers a way he can help them win.

Milo and the gang spend the entire day chasing after his doctor’s note that excuses an entire semester of absences, illness and shenanigans caused by Murphy’s Law.

Zack, Melissa, and Milo attend an opera performance with Amanda, but Milo accidentally ends up backstage and attempts to prevent any havoc from occurring.

It's career day and Milo is having a hard time deciding what his career should be. He tries to decide while visiting the water works, fire department, and hospital. But of course, everything goes wrong. Meanwhile, Dakota and Cavendish try and make sure a truck full of pistachios makes it to the pistachio warehouse.

Milo and Zack try to help Melissa overcome her secret fear of roller coasters.

Milo and Melissa share their most embarrassing stories, but Zack refuses to reveal his past.

A jaded science substitute teacher, Ms. Baxter, re-discovers her love of teaching after a life-altering day with Milo.

Cavendish and Dakota compete against two of the agency’s top operatives, Brick and Savannah, to impress their boss.

When Melissa’s dad drives her and Milo into town on a decommissioned old fire engine, chaos ensues.

Milo and Melissa finally tell Zack the story of the infamous Llama Incident.

When Cavendish and Dakota stop Milo from destroying a pistachio plant, they change the future. Pistachio plants become sentient and take over the planet, so Cavendish, Dakota and Milo must race through time to save the future.

Milo wants to get an autograph from his favorite actor, Tobias Toopanen, who is shooting a film in town.

Milo begins to sleepwalk through some nearby woods. Meanwhile, Cavendish and Dakota have a "ditch day" from pistachio duties after their ordeal with the Pistachions.

The students take a trip on the school yacht.

Elliot gets to see what the world would be like without Milo.

Milo, Cavendish, and Dakota travel back to 1965 and inspire the creation of Dr. Zone only to encounter a sinister plot to take over the world.

Zack doesn’t think anything about Halloween can scare him anymore, but he didn’t account for Murphy’s Law.

Milo, Zack, and Melissa—with help from Phineas, Ferb, Candace, Buford, and Baljeet—help conquer Murphy's law to stop a swarm of Pistachions.

In a similar vein as "Going the Extra Milo", Milo and Zack attempt to survive Murphy's Law while getting to school on a cold winter day while Bradley and Melissa bet on whether they'll make it on time again. Meanwhile, Cavendish and Dakota are forced to stand before the Time Council for their constant failures, resulting in their being fired and having their ability to time travel revoked.

Melissa and Zack become determined to get a good picture of Milo for school Picture Day after learning he's never had a good one due to Murphy's Law; but Chad misinterprets this as Milo being a vampire and recruits Mort to help him prove it. Meanwhile, Cavendish and Dakota get new jobs at P.I.G. (Paranormal Investigation Group) and try to capture a Yeti on camera to impress their new boss.

Milo and his friends and family decide to finally attempt to finish a board game.

Milo and Amanda get the chance to be on the latter's favorite TV show, Cake 'Splosion!, an extreme kids' cooking show.

Sara starts to go insane from Dr. Doofenshmirtz constantly invading her personal space, so he goes out with the rest of the Murphy family to try new things

Milo and his friends try to save the old clock at City Hall that Melissa's great-grandmother designed. Meanwhile, Doof tries to help the city by removing sidewalk gum under Agent P's supervision.

Doof shadows Milo to see how he navigates around Murphy's Law. Meanwhile, Cavendish joins an extraterrestrial conspiracy support group.

When his Uncle Cornelius asks for help on his farm, Zack seeks out to prove to a doubtful Milo and Melissa that a "city boy" like him can handle the job. Meanwhile, on a nearby farm, Cavendish and Dakota are assigned to pick up a fallen UFO piece from a farmer who wants to become famous in the tabloids.

Elliott gets hurt because of a Murphy's Law related incident, so Milo helps him with his second job as a dog walker. Meanwhile, Cavendish and Dakota discover an alien anti-gravity device and try to show it to Mr. Block for a promotion.

After discovering a boombox in the attic, Milo, Martin, and Grandpa Murphy go camping so Milo can undergo a family rite of passage to become a "Murphy Man". While the men are away, the Murphy women and Doof go to an art museum to celebrate the day without Murphy's Law, but Doof causes chaos in its place.

After an incident with a skydiving simulator, Milo, Melissa, and Zack are left in a cycle of falling and rising through the sky while Diogee tries to save them. Meanwhile, Cavendish and Dakota, while flying a plane and trailing a "Don't Litter Our Planet" banner, accidentally gain rivals in the form of Colonel Niblet and Lieutenant Tenant after taking the blame for Milo and his friends destroying one of their facilities.

Eons in the future, an elderly man tells his grandson how a sentient crockpot of goulash came to be and defeated an army of robot screech owls. Back in the past, Milo, his friends, and Doof attempt to protect Brigette's goulash from Murphy's Law and Doof's hand-held-inators.

Doof becomes inspired to find an "adventure buddy" to get over Agent P, and winds up joining Scott on a boat ride through the sewers.

Milo attempts to escape his room so he can go out for the day with Zack and Melissa. Elsewhere, Dakota teams up with Doof to find Cavendish, who's attempting to show various news outlets a crashed U.F.O. with a malfunctioning cloaking device.

Milo and Elliot accidentally get handcuffed together. Meanwhile, Zack and Melissa attempt to make a student film, but Doof messes everything up.

Six-year-olds Milo and Melissa meet for the first time, and Murphy's Law makes their first day of 1st grade a big adventure. Meanwhile, Dakota relates to Doof how he first met Cavendish while training to become time agents.

Milo, Melissa, Zack, Mort, Bradley, and Amanda get in trouble with a substitute teacher and get detention. Meanwhile, the killer cyborg bear from "Now I Am a Murphy" returns to track down Milo and get revenge on him.

Milo, Lydia, Coach Mitchell, and Scott get stuck in the Googolplex Mall elevator. Meanwhile, Doofenshmirtz and Dakota decide to finally attempt to search for Cavendish with the help of a "Cavenpus" clone made from Cavendish and Agent P's DNA.

Milo faces down a cosmic storm made of negative probability ions, while Melissa, Zack, Cavendish, Dakota, Perry, and Doof work their way through the alien populace to save their friend.