Alex'a sister Tanya turns up in San Francisco to visit her. She is with her friend Daniel, an African healer/shaman. He wants Alex to join them, to help him cure people normal medicine cannot. Her friends in the Legacy don't trust him and think there is more to him and how his powers work than he is letting on.

In New Orleans, Alex encounters an old college friend who is now a vampire. But when she is bitten she begins to transform into a vampire but the process will only be completed when she has taken her first human life.

Alex's grandmother travels to San Francisco to warn her of an evil spirit/Bocor thatis after her. She gives Alex a magic charm to protect her but falls pray to the Bocor's voodoo powers herself.

With her grandmother now in a coma Alex does the only thing she can think of to help her... she releases Daniel Euwara, a powerful spirit, from the prison the Legacy trapped him in (see 'Spirit Thief')and asks him to remove the curse.