As the city of Seattle revels at the Phoenix Fair celebrating the city’s rebirth post-COVID, the Grey Sloan doctors treat a patient who encounters illegal fireworks. Meanwhile, Bailey has her sights set on hiring new doctors, but she’s having trouble finding viable options. Owen and Teddy attempt to take the next step in their engagement, and Meredith has a surprising opportunity when she meets a dynamic doctor from her mother‘s past.

The crossover starts on Station 19 S05E01 Phoenix from the Flame (I).

Meredith seeks advice from Amelia. Meanwhile, Richard is reenergized as he takes teaching to a new level at the hospital, and Winston treats a patient suffering from kidney failure.

It's Thanksgiving, and while Meredith faces travel complications due to the weather, Nick steps in to help in more ways than one; Richard and Bailey seek out emergency surgeries; Amelia and Link reconnect.

Dr. Hamilton takes his frustrations out on Meredith, so Nick gives her a chance to blow off steam by scrubbing in on a surgery. Back in Seattle, Link and Jo take their kids to a fairytale theater performance that goes wrong. Bailey and Dr. Lin attend a recruitment fair in hopes of attracting more doctors to Grey Sloan but find themselves ill-prepared.

The doctors celebrate the holidays; Hamilton and Meredith prepare for a milestone on their project; Link wants to spend the holiday with Amelia and Scout as a family; Schmitt is faced with a difficult decision during surgery.

The Grey Sloan Memorial doctors grapple with the aftermath of the car crash that involved some of their own; Meredith works to save Dr. Hamilton's life. Levi is impacted from his latest loss.

Schmitt must face the Morbidity and Mortality conference. Meanwhile, Meredith convinces Nick to scrub in on a surgery in Seattle, and Jo faces her feelings.

Nick whisks Meredith away to his Minnesota cabin for a romantic weekend, leaving Winston and Maggie to care for Meredith’s children. Meanwhile, Amelia and Kai grow closer.

A former patient of Link’s, Simon, is in the ER with his pregnant wife; and Bailey receives an offer from Nick.

A dinner party is thrown at the sister house in Nick's honor. Meanwhile, Grey Sloan Memorial receives a victim of a brutal hate crime.

The blood shortage at Grey Sloan Memorial continues. Meanwhile, Meredith makes a risky decision regarding a patient, and Owen’s actions to help his fellow veterans come to light.

It’s Halloween night at Grey Sloan Memorial. Meredith and Nick try to spend some alone time together; Levi is stressed due to overworking, and Winston and Owen have the interns practice trauma training on a real cadaver.

Bailey and Addison take a road trip to volunteer at a family planning center, but a patient’s ectopic pregnancy leads to complications. Elsewhere, the interns play detective about Lucas’ relationship with Amelia, and Meredith catches up with Jackson on a trip to Boston.

Simone is met with a life-changing decision upon the return of someone from her past. Blue shadows Maggie on a risky procedure, while Jo and Link tend to a pregnant woman. At the intern house, Lucas and Mika throw a party filled with surprises.