As Sykes begins his end game, the agents discover that Helena is still alive... and teaching high school literature. Meanwhile, Jane reveals the full extent of her plan but one agent will lose their life carrying it out.

Pete and Myka race to stop Sykes from using his own cache of artifacts to destroy them and the Warehouse.

While the team deals with the news that Warehouse 13 is moving, Mrs. Frederic has them load their greatest memories of their missions into an artifact for future generations.