The whole team investigates the crime scene of an indoor amusement park when a young girl is found dead in the bathroom. They must track down the relentless man responsible for the heinous crime quicker than usual, as everyone on location has been detained until they can be cleared. What looks to be like a regular attempted kidnapping turns out to be much more than any of the detectives had bargained for.

A woman is killed during a posh party at an exclusive waterfront estate when a man opens fire on the proceedings from a cigarette boat. When a former con is arrested, he acts as his own lawyer and proves to be smarter than he appears. Complicating matters is the fact that the leading witness in the case is the dead woman's 10-year-old son, whom Horatio wants to protect, refusing to let him testify.

An 18-year-old girl is stabbed to death in a bathroom of a popular Miami nightclub. Horatio learns that the victim was an investigative aide working for Alcohol Beverage Control and was monitoring underage drinking. As Horatio interviews the club's owner, an unknown man drives by the club, sees that the police are there, and crashes his car while fleeing the scene. However, the case gets more complicated when they discover another murdered victim inside the car. DNA from the second victim's watch ultimately leads them to a day spa where the services may not be entirely legal. Meanwhile, Calleigh and Ryan work together to determine whether an insecure and underage teenager at the club that night had anything to do with the murder.

As a huge tsunami heads directly towards Miami, a ten-hour warning gives citizens just enough time to evacuate the city. In the chaos, two people are killed in a parking lot and the evidence leads Horatio to discover a plot to rob a bank timed to take advantage of the evacuation. However, as the CSIs close in on the robbery already in progress, they find that it's a more elaborate crime than they previously thought. In the wake of the storm, Ryan and Alexx discover a body washed up from a local cemetery that may have a different cause of death than originally recorded. Meanwhile, Horatio suspects that Yelina is being physically abused by her boyfriend, IAB's Rick Stetler.

When a woman is killed in what looks like a carjacking, the CSIs talk to her husband, the oldest of the three brothers who run their lucrative family business. However, when it is revealed that the victim had a gambling addiction that could have bankrupted the company, the team must follow the evidence to find the killer. Meanwhile, Alexx hires a recovering alcoholic as a body hauler and must investigate when he is accused of stealing from the dead.

The CSIs uncover a complex counterfeiting operation after a bellboy is found murdered at one of Miami's hottest hotels. The luggage that the deceased bellboy had been loading, as well as a heist of a special paper that money is printed on, leads the CSIs to uncover a complex counterfeiting operation. It's cruise season in Miami, which means that the population of Miami swells, giving the team even more suspects to the murder. Meanwhile, Calleigh must investigate when a woman goes missing, and is later found dead, after she and her husband attend a hot and flirty "friction" party.

Someone uses a laser light to blind a pilot and bring down a jet, which carries $1.2 billion in checks to be delivered to banks on the eastern seaboard. The crime scene evidence reveals a victim, a young fundraising socialite, who was inside the plane but killed prior to the crash. Now, although the team has little to work with since the victim's wealthy family is opposing an autopsy, Horatio must follow the money trail. Meanwhile, Calleigh works on the case with her ex-boyfriend, Detective Hagen, and their romantic history could cause problems for both of them.

Horatio's life is changed forever when he learns important information about his deceased brother. Horatio must now figure out what to do with this information about his brother, Raymond, and whether or not to tell Yelina. Meanwhile, the team investigates when a woman is murdered at a crowded bar after she's approached by a female employee of a service that helps men pick-up women. Also, when Delko loses his badge after some reckless behavior and it's used in a crime, he must locate the badge before it's used again.

An axe murderer on death row is given a stay of execution just moments before it was to take place, on the grounds that there may have been tainted DNA analysis used at his trial. Now, without using any DNA evidence, the team must race against time and reexamine all of the physical evidence in the case, just as they get a call on a new double murder that looks suspiciously like the case they're working on.