With the drug trade out of control in Las Vegas Lt. Farlowe convinces the brass that it is time for new methods with a different breed of cops. He pulls together the wildest and best of the Vegas force to form a super-secret strike force, he calls the North Town Narcotics Bureau, dubbed The Nasty Boys by local press. The Nasty Boys begin taking the drug dealers rings apart apiece at a time. Payday, the leader of one of the drug gangs, is not willing to simply wait and let the Boys come to him. He takes his fight to them head on, leaving Lt. Farlowe dead.

A group disguised as the Boys hits a crack house leaving ten bodies in the wake and the Nasty boys locked in the sights of Internal Affairs. With the police brass breathing down his neck Krieger refuses to divulge the names of the Nasty Boys. It is not long before the mastermind behind the Nasty Boy's problems is revealed as an old enemy, Payday, last seen in the pilot movie. Payday killed the Boys first leader and now the Boys are out for a little payback.