After renowned weapons dealer, Xerxes, hides the formula to a dangerous and lethal biological weapon in a painting, Shaw assigns Steven and Samantha the task of traveling to Tuscany to secure the painting and capture Xerxes. When the assignment requires Samantha to assume a previous cover and partner with Steven's enemy, Clive, the Blooms learn that teaming together is not as easy as they thought. Meanwhile, Hoyt's attraction to Clive's assistant proves to be instrumental in finding the culprit.

When American currency engraving plates are stolen from an armored truck, Steven and Samantha must recover them before the terrorist who stole them counterfeits American money. Traveling to Croatia, the situation gets complicated when the Blooms find themselves working together with Steven's estranged brother Gary. Meanwhile, Leo helps Lizzy make a decision about her future.