Andreas Solowiechek, a member of a Communist trade delegation, is arrested after assassinating a U.S. Senator, Townsend. Townsend's backer, McMillan, is rallying his supporters for the U.S. to break off all trade talks with the Russians. It is believed Solowiechek wasn't working on the orders of his government, so the IMF team have to break him. Rollin becomes the assassin's cellmate, and arranges to be handcuffed to him. Rollin then fakes an escape, and threatens to kill Solowiechek. The assassin promises that his backer can Rollin money. Meanwhile, Dan has pretended to be an artist and got into McMillan's house, leaving a camera behind hidden in his art box. Rollin and Solowiechek confront McMillan, and the latter admits that he arranged for Townsend to be killed so as to become a martyr to his cause, unaware that his words are being transmitted on national TV.

Jim and a female agent pose as scientists who have invented a new drug in order to replace a real drug that turns people into willing slaves.

As Barney taints the water system with a mind-numbing drug, Jim is captured and put on trial, where he must discredit an enemy scientist.

James Read, an enemy agent, is posing as an analyst to get to a top-secret U.S. missile guidance system being tested and steal the plans - the IMF must have him take back fake plans and unwittingly pass on the incorrect information to his superiors. Dana takes the place of Read's contact and he and fake boss Jim fake a romantic relationship so Read can get blackmail photos and use them to turn over the system. Read tells Dana of his plan to kill Jim, but before she can warn Jim, Dana is kidnapped by Hecker, a psychopath who believes Dana is a former girlfriend he killed. After Willy saves Barney from a firetrap meant for Jim, Paris and Barney manage to rescue Dana and alert Jim just in time to avoid a rigged car, convincing Read he's in the clear with the guidance system.