In 1987, in Japan, a boy named Jotaro Kujo has willingly turned himself into jail, refusing to leave. Jotaro's mother, Holly, requests help from her father, Joseph Joestar, who travels to Japan alongside an acquaintance, Mohammed Abdul.

Jotaro heads to school and encounters a mysterious transfer student named Noriaki Kakyoin.

Jotaro is able to defeat Kakyoin. He takes the wounded Kakyoin back to his house, hoping to get some information about DIO.

If they do not defeat DIO within 50 days, Holly could die - Jotaro and crew head to Egypt, where they think DIO is hiding. While on the plane, they run into another one of DIO's assassins.

DIO's next assassin, Polnareff attacks Jotaro and crew, Abdul faces him with his Magician's Red.

With a new person in their party, they head to Singapore with the boat the Speedwagon Foundation provided them, during their journey Jotaro is targeted by an enemy Stand from within the water.

A giant ship shows itself. On board, they realize they can't seem to find a crew, but an orangutan.

Arrived in Singapore, Jotaro's group stays at a hotel individually. A new Stand owner who is known as "Devo the Cursed" is awaiting Polnareff in his room. Devo's Stand increases its power as its user's hatred towards the opponent increases. Polnareff gets into a desperate situation as he starts fighting front. Does Polnareff have a chance to win the battle against Devo who keeps attacking him in a cruel and brutal way?

Joseph uses Hermit Purple to create a message using the TV, which tells them that Kakyoin is a traitor.

The group travels to India. In a restaurant Polnareff is attacked by a mysterious Stand that is inside a mirror.

In an effort to save Polnareff, Abdul is injured by the enemy. Then J. Geil's Stand, Hanged Man attacks.

The group heads toward Varanasi. On the way, Joseph realizes his arm is quite swollen.

Jotaro and the others head toward Pakistan in a car. Polnareff is driving the car on a very dangerous mountain road, and recklessly passes a slow moving vehicle that was in front of him.

Jotaro and the others successfully survive another attack from the enemy Stand users and make it into Pakistan. However, they decide to find an inn at a nearby village because of the dense fog they suddenly hit. The village they get to is rather quiet and all of the inhabitants seem rather odd.

Polnareff finally realizes that Enyaba is another assassin from DIO. He tries to warn the others, but Enyaba's Stand, Justice, has the ability to take control of people's bodies and corpses, and he is pursued. The whole village had already been under Enyaba's control.

After surviving Enyaba's attack, Jotaro and crew make it to Pakistan's capital, Karachi. There, they encounter DIO's next assassin, Steely Dan. Following DIO's orders, Steely Dan ruthlessly kills Enyaba in front of them. Jotaro and the others can't help but feel conflicted about that happening, and end up in a battle with Steely Dan.

Steely Dan's Stand, The Lovers, has entered Joseph's brain. Dan puts himself at an advantage, with having Joseph's life on the line, and tells Jotaro to do various things for him, knowing Jotaro has no choice but to obey. Meanwhile, Kakyoin and Polnareff also enter Joseph's brain with their Stands and find the Stand that is using brain cells as food.

Jotaro and the others continue their journey through the desert, trying to get to Cairo. They travel with camels and can't shake the feeling that someone is following them, but no one is in sight. Traveling in the killer heat, they realize that it's still bright out at 8pm and the sun is actually rising rather than setting.

Kakyoin is dreaming and dreams about being in a strange amusement park, where he encounters the Death tarot card. While in the dream, he witnesses Death 13 cut down a dog. Kakyoin wakes up screaming, but can't remember what his bad dream was about.

Kakyoin tries to convince the others that the baby is suspicious, but that backfires and his friends start to doubt his sanity. Kakyoin then tries to convince them that he's not crazy, and shows them his arm that has "Baby Stand" carved into it... but that just makes them believe he really is crazy. Kakyoin then tries to use his Stand to attack, but is knocked out by Polnareff. Eventually, Jotaro and the others wake up in the nightmare and the truth finally comes out.

While on an island on the edge of the Red Sea where Mohammed Abdul's father is said to live, Polnareff uncovers a magic lamp and its genie Cameo offers him three wishes, although all is not as it seems. 

Polnareff must find out a way to escape the attacks of Cameo and his Stand Judgement who has apparently turned his sister Cherie and Abdul into zombies.

Jotaro and the others obtain a submarine as a new means of travel. Through the Red Sea, they try to head toward Egypt where DIO awaits. Using the sonar to detect any threats on the outside, the submarine quietly dives in. They however realize that if they're attacked underwater, there is nowhere to escape, so they are on their guard. Finally, when they are about to surface, a coffee mug that was in the cabin transforms and cuts off Joseph's artificial hand.

The group must find a way off of the submarine and away from the attacks of High Priestess. 

Jotaro's group encounters N'Doul's Stand "Geb", and Iggy's "The Fool".

The group's encounter with "Geb" and "The Fool" continues.

As the Joestar group arrives in Aswan they encounter Oingo's Stand "Khnum" and Boingo's Stand "Thoth".

Jotaro's group encounters the Stand "Anubis".

The encounter with the Stand "Anubis" continues.

Jotaro and the others arrive in Luxor. While heading there, Joseph notices an electrical outlet in a rock. Obviously fascinated by the electrical outlet in the rock, Joseph gets closer, and he gets shocked.

Due to the powers of an enemy Stand, Joseph's body becomes magnetised. While chasing after the woman that seemed to be the Stand user, Abdul also touches the electrical outlet and becomes magnetised as well.

While Joseph and Avdol were fighting with Mariah, Jotaro gets concerned that they haven't shown up yet, and goes to look for them around Luxor. Then, Polnareff senses someone following them and confronts the man.

Because of the power of Alessi's Stand, Set, Polnareff is turned back into a child. The one who came to his aid amidst his confusion was a woman named Marena. However, Alessi's evil hands followed Polnareff into her house.

After a long journey, Jotaro and the others finally reach Cairo. They go to a cafe and ask if anyone knows where DIO's mansion is located by showing the picture around. Then, someone says that they have seen the building before.

Souls are on the line as a game of poker continues.

Hol Horse arrives at Cairo in order to pursue Jotaro and the others. He has joined forces with another partner and is after the lives of Jotaro and crew once more. That partner, is none other than Boingo.

Hol Horse and Boingo followed Jotaro and the others to Cairo and as Boingo's book said, Hol Horse stuck his fingers into Polnareff's nose... but he didn't know what to do from there. Then Jotaro and the others, who were looking for Polnareff, show up, but things seem to be going the opposite way of the premonition.

Jojo and the others continue to look for DIO's mansion in Cairo. Following Abdul's advice, they have a beggar look for the mansion and wait. Meanwhile, Iggy, who is wandering the city alone, gets confronted by two large dogs. The dogs are freaked out by Iggy's power, and decide to go after a bird that's at a nearby mansion instead. However, as soon as the dogs go into the mansion, they are impaled by a giant icicle. Iggy is shocked by the occurance, and sees a falcon appear...

Iggy ends up in a battle to the death in the sewers against the falcon that guards DIO's mansion, Pet Shop. Pet Shop shows no mercy, and goes after Iggy at a frightening speed. Iggy, despite being injured, runs into the river, making a dome made out of dirt to shield him. However, he underestimates Pet Shop's abilities, and...

Despite Iggy's injuries, Jojo and company finally make it to DIO's mansion. Once they entered, a butler named D'Arby the Younger was awaiting their arrival. The younger brother of the defeated D'Arby the Elder, he immediately shows off his Stand, Atum's power.

The battle for souls with D'Arby continues. Kakyoin challenged D'Arby to a race game, but ends up losing and D'Arby steals his soul. Before Joseph really has time to react, Jotaro picks the next game.

The baseball match with D'Arby continues within DIO's mansion. For some reason, Jotaro starts declaring his pitches to D'Arby. D'Arby finds Jotaro's actions strange, but still believes he has the upperhand because of his Stand's abilities.

After a long, hard journey, they are faced with a sudden goodbye of a friend. Because it's so sudden, Polnareff can't control his emotions. He starts brandishing his sword toward the unseen enemy with very little success.

Polnareff is pushed to his limits with Vanilla Ice's merciless attacks. He finally awaits death, but is saved at the last minute by the dying Iggy. Iggy uses the last bit of his energy, but his Stand is obviously losing power. Polnareff then stabs Vanilla Ice in the head. Despite showing resilience to the attacks so far, Vanilla Ice is finally destroyed.

Polnareff encounters the Stand "The World".

The group tries to identify DIO's Stand.

The fight continues.

The final battle!

Koichi arrives in Italy on a mission from Jotaro to find Giorno; they meet haphazardly when Giorno steals Koichi's luggage, and the ensuing chase leads Giorno into a Stand battle with the gangster Leaky Eye Luca.

Faced with Bucciarati's Stand, Sticky Fingers, Giorno desperately uses Gold Experience to defend himself.

Giorno is interviewed by a strange man to enter the Passione gang and achieve his dream of becoming a "Gang-Star".

After apparently failing Polpo's test, Giorno is attacked by his stand, Black Sabbath, who tries to pierce his soul with a stand arrow.

News of Polpo's death reach the organization, along with word that he had a huge fortune hidden somewhere. Meanwhile, Giorno meets Bucciarati's gang.

Bucciarati and Abbacchio are the only members of the gang left in the yacht. They have to find out where the enemy stand is hiding and how does it work.

After defeating Zucchero, the gang realizes that he has already told someone else where they were going and why.

Mista chases a Passione member named Sale to stop him from finding Polpo's treasure.

After being promoted to capo, Bucciarati and his gang are tasked to protect the boss' daughter.

Narancia discovers that he is slowly shrinking due to the wound Formaggio's stand, Little Feet, had inflicted on him.

Formaggio traps the now miniature Narancia beneath his foot and attempts to interrogate him, but Narancia resists. A flashback shows Narancia's early life on the streets and his rescue by Bucciarati.

In order to protect Trish from the Hitman Team, Bucciarati and crew's second mission from the boss was to go find a key in Pompei for some kind of vehicle that should aid them later on. Following orders, Giorno, Abbacchio, and Fugo head to Pompei to retrieve the key. When they get there, Fugo notices a suspicious shadow reflecting in a mirror that happened to be placed on one of the pillars there...

The person hiding in the mirror was Illuso from the Hitman Team. Fugo ends up being dragged into the mirror by Illuso's Stand, Man in the Mirror. Fugo then summons his own Stand, Purple Haze. Despite Giorno wanting to find Fugo, Abbacchio decides to go look for the key, since that was their mission. However, once Abbacchio finds the key, he also gets dragged into the mirror world...

"Take Trish to Venice." With their next order from the boss, Bucciarati and his crew head to Naples Station. "Use the key at the water fountain with the turtle on the 6th platform." They find the water fountain, but can't find the place to use the key. Meanwhile, Proscuitto and Pesci from the Hitman Team follow Bucciarati and the others to Naples Station. Bucciarati figures out the mystery behind the key and gets on the express train to Florence, and Proscuitto and Pesci follow.

The Grateful Dead slowly begins to age everybody on the train. With his teammates affected, Mista goes alone to confront the enemy, only to encounter Pesci and his Beach Boy.

Number Six from Sex Pistols manages to warn Bucciarati about the enemies and fights back, but The Grateful Dead's powers are taking a toll on him. Bucciarati steels his resolve and throws himself out with Prosciutto out of the train that's going 150kph. Barely hanging onto life, Prosciutto uses The Grateful Dead again. Pesci decides to take Prosciutto's resolve to heart and attacks Bucciarati.

After defeating Proscuitto and Pesci, Bucciarati and the others head to Venice in a car. Melone from the Hitman Team finds some of Bucciarati's blood at the scene where the train had stopped and then activates Babyface. The powerful remote-control Stand created by assaulting a woman on the train then goes after Bucciarati.

Using Babyface's Stand's ability to turn human parts into other things, Giorno uses his Golden Wind to make parts for the human body. He rebuilds his own body and fights back. Meanwhile, another member of the Hitman Team who's also after Trish, Ghiaccio, was trying to regroup with Melone and was driving to Giorno's location.

Ghiaccio's Stand, White Album is able to envelop him like a bodysuit and able to freeze everything around him to extremely low temperatures. Giorno and Mista somewhat make it to Venice, despite being partially frozen by Ghiaccio. But in order to try to get away from Ghiaccio, Giorno drives their car into the canal and they get stuck. Mista tries to sacrifice himself, but Giorno tells him that what's important right now isn't for him to sacrifice himself but for him to have resolve.

Mista and Giorno were able to defeat Ghiaccio. They then confirm the mission on the disc and head to the location they're supposed to take Trish. Bucciarati goes up the tower with Trish, but while they're in the elevator, Trish suddenly disappears. Bucciarati then realizes what the boss's true motives are.

Bucciarati finds out that the boss's true motive is to eliminate Trish because of her relationship with him, causing him to betray the boss and save Trish. Meanwhile, Giorno feels something bizarre is going on as they waited for Bucciarati's return. The boss's Stand, King Crimson rises.

Because of their own wills and their sense of justice, Bucciarati and the others end up betraying the organization. Trish also wants to find out who her father truly is, so she tells the others that her mother met her father in Sardinia. They all decide to have a meal in Venice before they leave and Narancia is suddenly attacked by a Stand. The boss's own personal elite guard was now on the move.

The Stand that attacked Narancia was named Crush and belonged to Squallo, a member of the boss's elite guard. On top of that, Narancia suddenly can only say the exact opposite of what he's thinking, thanks to the ability of Talking Mouth, the Stand of Squallo's partner, Tiziano. Using Narancia, Squallo and Tiziano throw the team into chaos. The two elite guard members put Narancia in danger, but he boldly faces them so they can get out of Venice safely.

After defeating Squallo and Tiziano, Bucciarati and the others head off to Sardinia to find out about the boss's past. They head to Marco Polo International Airport in order to get a jet, but a strange man was following them. Mista manages to kill the strange Stand user before they're able to call upon their Stand. Even though they're a bit put off at how simple that was, they get onto the jet and fly off. But once they're on the jet, Giorno hears a weird noise...

Trapped in the cabin of a flying plane with Notorious B.I.G, Trish has noticed that Giorno's brooch is turning into a brand new hand that will allow him to regain his powers. However, the movement of the transformation is attracting the enemy Stand. As the plane approaches the Tyrrhenian Sea, Trish must now try to protect both the hand of Giorno and herself from Notorious B.I.G.

On the island of Sardinia, a boy named Doppio is searching for Trish and the others on orders from Passione's boss. But Doppio has a dark secret, one that becomes apparent when he encounters Risotto of La Squadra.

Doppio, the alter ego of Passione's boss, continues to fight against Risotto and his iron controlling Metallica. Doppio struggles against the powerful assassin, but is armed with King Crimson's Epitaph, which allows him to see the future.

In the aftermath of the battle between Risotto and Doppio, Abbacchio uses Moody Blues to try and uncover the boss's identity. But the boss is adamant about keeping his identity a secret and executes his next gambit against the group.

After his death, Abbacchio was able to leave the others a copy of the boss’s face and fingerprints with Moody Blues' replay. The others try to find out who the boss is with the fingerprint and suddenly get contacted by someone. The mysterious man tells them that the boss’s name is Diavolo and tells them that the secret behind defeating him lies in the arrow. Bucciarati and the others head to Rome to meet him.

The gang are under attack by the last two members of the Elite Squad. Cioccolata uses his Green Day to spread a toxic mold over the island while Secco uses Oasis to swim through rock for stealth attacks, leaving the gang in a pinch.

While Bruno stays on the ground to fight against Secco's Oasis, Giorno and Mista head upwards towards Cioccolata to stop the power of his Green Day. But Cioccolata has another dangerous trick up his sleeve, pushing the two into a corner.

Bruno and Secco are both racing towards the man at the Colloseum whilst trying to kill each other.

Bruno unknowingly leads Doppio to the Colosseum while the rest of the gang is searching for their leader.

Everyone wakes up from a deep sleep to discover their souls have been swapped.

The gang desperately tries to reach the Stand arrow whilst looking for Diavolo.

Everyone continues to desperately chase after the Requiem in order to obtain the Stand arrow. Diavolo's soul is then forced to show itself, but he will not quit until he obtains the arrow for himself.

The Stand arrow's rightful owner is finally revealed.

Giorno achieves his dream and destiny of becoming a Gang-star.

In the past, Bruno and his team investigated the mysterious death of a girl and how it ties into the power known as Rolling Stones. And in the present, the final fate of Giorno and the gang is revealed as Golden Wind comes to a close.