A competing minimart issues a competition to see who can bag items faster, Zack and Cody accept the challenge. Meanwhile, Mr. Moseby's niece Nia is goofing off with London.

Zack and Cody rent out London's Suite while she is out of town so that Stacie, a cute girl from school can have a sleepover birthday party at the hotel.

When Zack and Cody invite Arwin over for dinner he won't seem to leave. Carey is getting annoyed at him so she forces Zack and Cody to make him go. Meanwhile, Lance dumps London and she wants to find a way to get back with him.

It's the first day of high school for Zack and Cody. For the first time, London has to attend public school.

Zack tries to negotiate a better contract for Carey as the Tipton's nightly singer. Nia and London both want Cody's help with their science projects.

Maddie is back and is not getting along with Nia, while Estaban is not getting along with Patrick, and the rest of staff aren't getting along either. So, Mr. Moseby hires a professional to help the team get along. Meanwhile, when Zack causes some customers to leave, he and Cody schedule a bug convention at the Tipton to make it up to Mr. Moseby. However, due to his fear of bugs, he accidentally releases the bugs into the Tipton.

Zack tries out for the high school basketball team but realizes there's some stiff competition, the kind he didn't face in middle school, and worse yet, the giant, in-your-face Coach Little (Michael Clarke Duncan). Meanwhile, when they're rejected as cheerleaders, Cody and London form their own cheerleading squad with the help of Mr. Moseby.