When a body is found missing a heart, Liz and Ressler join forces with Samar Navabi to investigate Dr. Covington's operation. Red and an associate try to take advantage of an opportunity in Indonesia.

Red thinks a dangerous sociopsychological experiment may be taking place when several previously nonviolent citizens become killers. Red has a complicated proposition for Naomi and her husband.

Liz and Red take a detour to the Midwest. Ressler, Aram and Samar accidentally uncover what could turn into a global food crisis. Cooper seeks help from an unexpected source.

Red enlists a task force to locate the Djinn, an enigmatic woman who fulfills revenge fantasies. Red and Liz believe the Djinn can lead them to the Cabal and help them exonerate Liz.

Red and the FBI come together to protect Liz when a huge reward for her capture attracts attention from assassins.