After decades apart, Jamie and Claire finally reunite and rekindle their emotional and physical bonds. But Jamie's new business dealings jeopardize the couples' hopes for a simple life together.

Claire follows her conscience as a surgeon, even though it could put her and Jamie's lives at risk. At the same time, Jamie attempts to evade the reach of the Crown as it representative closes in on his illegal dealings.

Claire and Jamie leave Scotland, sailing to the West Indies on an urgent quest. But when the superstitious crew looks for someone to blame after a string of bad luck, rescue comes from an unlikely source.

Claire races to discover the source of an epidemic aboard a disease-stricken ship before hundreds of sailors die. And as Jamie locks horns with Captain Raines, Fergus finds himself torn between loyalty and love.

After making a leap of faith, Claire washes up on an island where survival is her only option. Navigating treacherous waters crippled the Artemis, so Jamie devises a joyful moment for his crew in the midst of setbacks.

The Artemis finally reaches Jamaica bringing Jamie and Claire much closer to their goal. During a ball on the island, the Frasers encounter old allies, as well as former adversaries who threaten to derail their mission.

Claire plays a game of cat and mouse with an old adversary as she searches for young Ian. The Frasers race through the jungles of Jamaica to prevent the unthinkable.

Claire and Jamie cross paths with Stephen Bonnet, a pirate and smuggler who enlists their help. Claire illuminates Jamie on some of America's history, leading him to wonder if it's possible for them to lay down roots.

Having been led by providence to Fraser's Ridge, Jamie, Claire and Young Ian begin to build a home in the Blue Ridge Mountains. In the 20th Century, Roger tries to reconnect with Brianna.

Roger's diligent search for Brianna pays off when he finds her in Wilmington, but their romantic reunion comes to an abrupt halt when she discovered pertinent information that he intentionally kept from her.

Jamie, Claire and Young Ian embark on a long uncertain journey to rescue Roger, while Brianna forges a friendship with one of Jamie's old friends as she fends off Aunt Jocasta's attempts to secure a husband.

Brianna confronts a violent figure from her past in an attempt to cope with her trauma. Roger befriends a fellow captive and endeavors to escape the Mohawk Village, while Fergus and Marsali plan a dangerous mission.

Following celebrations in honor of Brianna and Roger's wedding, Governor Tryon reminds Jamie of his obligation to hunt down and kill Murtagh Fitzgibbons.

As Jamie continues to hunt Murtagh with the aid of the zealous Lieutenant Hamilton Knox, he's forced to consider whether or not he's on the right side of history.

The growing Regulator threat forces Jamie, Claire and Roger to embark on a mission to raise a militia.

Roger leads Jamie's militia to the trading post of Brownsville and finds himself embroiled in a bitter feud. Jamie and Claire arrive to find that Roger's unusual strategy may have cost them the loyalty of the militia.

Jamie and his militia arrive at Hillsborough to learn that Governor Tryon has proposed a rather unorthodox solution to deal with the threat posed by the Regulators and to resolve the growing political crisis.

At Jocasta's wedding, Jamie learns Tryon's true motivation for ending the Regulator threat.

The Regulator Rebellion reaches a boiling point, forcing Jamie to face his fear and confront the consequence of his divided loyalties.

The Frasers must come to terms with all that has changed in the aftermath of the Battle of Alamance Creek. Brianna tries to help Roger overcome the trauma he has endured. An unexpected visitor arrives at the Ridge.

When Jamie is bitten by a venomous snake, Claire fears she may not have the resources to save him. Jamie asks Roger to complete an important task in the event of his death.

Jamie and Roger implement their plan to eliminate the threat looming over them, but it goes awry. Brianna is forced to confront her greatest fear and fight for her and her son's lives.

A revelation about Jemmy forces Roger and Brianna to choose between staying in the eighteenth century and returning to the safety of the future. Jamie finds that unrest in the backcountry has given rise to a new power.

Claire struggles to survive brutal treatment from her captors, as Jamie gathers a group of loyal men to help him rescue his wife. Meanwhile, Roger and Brianna's journey takes a surprising turn.

Jamie's authority is tested when an old rival from Ardsmuir shows up to settle on the Ridge. Claire finds a new way to cope with the trauma of her assault by Lionel Brown.

Jamie struggles with his first request as Indian Agent. Roger presides over an unusual funeral. Marsali gives birth. However, the joy is short lived when a discovery is made.

Fergus worries about his new son's quality of life when the baby is bullied by superstitious Protestants. Claire performs surgery on Tom's hand.

While visiting the Cherokee, Ian encounters a man from his past who dredges up painful memories of his time with the Mohawk. Jamie meets an Indian Agent who challenges his convictions, causing him to re-evaluate.

Claire and Jamie experience the rising tensions in the colonies first-hand when they attend a Loyalist event in Wilmington in honor of the Scottish heroine, Flora MacDonald.

A dysentery epidemic spreads on the Ridge, and Claire falls deathly ill. She is almost recovered when the Christies arrive and drop a bombshell. As nefarious rumors spread like wildfire on the Ridge, tragedy strikes.

Claire struggles with her demons as a nefarious rumor begins to spread on the Ridge. Tensions rise as the residents fear there is a dangerous person in their midst.

Richard Brown and his Committee of Safety arrive to arrest Claire for murder. However, due to the rising political tensions in the colonies, Brown's plan to find a judge for a trial does not go as expected.