When Oliver's dad starts to wonder where he's going after school, Oliver says he's doing a play about Frankenstein.

Kaz boldly asks the most popular girl in school to the upcoming school carnival but is rejected, and tries to save face by claiming he already has a girlfriend. Much to Oliver's chagrin, Kaz invites Skylar to accompany him to the carnival, her first venture into the "normo" world, in hopes of convincing everyone that she is his girlfriend. Meanwhile, Alan tries to prove his worth to his uncle Horace by attempting to cure Titanio, a superhero with amnesia.

Alan is put in charge of the hospital for a day, but he abuses his power and makes life miserable for everyone.

Tension is high at Logan high, and Kaz becomes suspicious that his substitute teacher is actually Dr. Wrath in disguise, a supervillain who feeds on negative energy. While Kaz is determined to get to the bottom of it, Oliver helps Alan get over his aversion to normo food.

Kaz launches a superhero fantasy league at the hospital. The heroes become obsessed with their fantasy stats and only perform saves and defeats that will boost their standings in the league.  Minnesota Vikings’ running back Adrian Peterson guest stars as himself.

When Horace complains that comic book sales are down, Oliver and Kaz join the writing staff to help spice up the books. However, the boys' altered versions of the stories cause problems in the superhero community.

Horace introduces the boys to an all-powerful device that looks like a pen, but can bring any illustration to life. Panic ensues at the hospital when the device goes missing.

Kaz and Oliver suspect that there could be a hospital mole that is working with the Annihilator.

A man from the future visits the boys and reveals himself as Kaz twenty-five years from now. Future Kaz warns the boys of an evil villain wreaking havoc on the future.

Gulliver and Chaz stumble into Mighty Med and Horace hires them, threatening Oliver and Kaz; Skylar makes a suggestion box to boost staff morale.