A female villain named Femme Fatale teaches the girls' to be sexist, so she can get away with crimes.

The Professor tries to spend time with his daughters, but they fight crime to much. To solve the problem the Professor creates a power suit, so he could fight crime and spend time with the girls'.

After receiving a dollar from the Professor, Buttercup gets hooked and steals other people's teeth for the tooth fairy.

The girls find an injured squirrel and Bubbles gives it Chemical X. This creates a super powered pet squirrel.

It's Valentine's day and The Powerpuff Girls try to hook up Ms.Keane and the Professor together.

When the Mayor finds the deed to Monster Isle the monsters move to Townsville causing havoc between monsters and humans.

There's a new Powerpuff Girl in town...or so she would have you think! Her fiendishly foul plot: to trick Santa into turning her into the fourth Powerpuff Girl! (And, in the process, make him believe the Powerpuffs have been very, very naughty!) Now, Bubbles, Blossom, and Buttercup must explode into a Yuletide tornado of bad-girl-thwarting action to put Princess in her place—and keep Christmas from disappearing forever!