Halstead and Marcel facilitate a trans-organ exchange. Asher and Cuevas help a sexual assault survivor. Choi and Archer treat a patient whose case could expose a fraudulent doctor.

Goodwin and Charles clash as negotiations drag on between the administration and the custodial workers' union. Asher fights to keep a mother and her newborn baby together.

Dr. Song launches her pilot program, giving the E.D. a technological facelift. Archer clashes with Charles on a patient faking paralysis. Archer helps a pregnant mother with a heart condition.