Ikki is about to follow his friends, but Pandora warns him that if he enters the path, he will be destroyed, since his Cloth is not bathed in Athena's blood. The six final Specters follow them. Pandora explains that 13 years ago, she lived a peaceful life in Heinstein Castle, before it became Hades' Castle. She lived with her parents, servants and many pets. One day, she found an old shed, locked for 200 years. Curious, she went inside, and found a box with Athena's seal. She opened it, releasing two deities, Thanatos and Hypnos, gods of Death and Sleep. They tell Pandora that her mother will give birth to Hades' soul and order her to take care of it, giving her the power to control the Specters and promising her eternal life. When Hades' reincarnation arrived, everyone except Pandora died in the castle. That was also the reason she went after Shun long ago. After meeting Ikki and the Saints, she realized what Hades promised was a lie and decides to help him, by giving him a necklace that will let him travel to the Elysium Fields safely. Pandora then mysteriously dies, for betraying Hades, but not before warning Ikki of Thanatos and Hypnos, gods and Hades' most loyal servants. The six Specters appear and they are killed by Ikki. With their deaths, all 108 Specters have died. Ikki places the rosary on Pandora's body, promising to avenge her. With his Phoenix wings, Ikki heads to the Elysium Fields. Nymphs warn Thanatos of a "demon" who entered the fields. The god investigates, meeting Seiya, who tells him Saori died. Hypnos, Thanatos' twin brother, appears, and reveals that Thanatos killed Pandora for helping Ikki. However, Hypnos has not killed Saori. Saori is in an urn, located outside a tower where Hades' body is located. Hypnos put her in a deep sleep, and the urn absorbs the blood of its victim. When the urn turns completely red, Saori will die. Seiya rushes to her rescue and Thanatos tries to stop him, but Seiya dodges the attack and counters while running towards Saori. Thanatos finally hits Seiya, destroying his wings. Meanwhile, Shaina, reunited with Marin, Jabu, Ichi, Ban, Geki, Nachi and Kiki, asks Marin where she was. Kiki then brings the mysterious girl from before. Marin reveals the girl's identity: Seiya's long-lost sister, Seika. Seiya hears his sister's voice, and gets up again, attacking Thanatos with his Comet Punch.

Aiolos, Dohko, Camus, Shaka and Aiolia's spirits sent their Cloths to help the Saints. Thanatos deduces that Poseidon sent the Cloths to the Elysium Fields. Back on Earth, Sorrento, who is travelling with Julian Solo, senses Poseidon in Julian's body. He tells Sorrento that he has sent the Gold Cloths, though still sealed, in order to help the Bronze Saints and also deduces the Grand Eclipse is launched by Hades, attempting to rule the Earth. Julian comes back to his senses and Poseidon returns to his eternal sleep. Seiya and his friends launch their signature moves against Thanatos at the same time, but they are ineffective, as the evil god destroys the Gold Cloths. Seiya begins to lose hope, but Saori speaks to him, urging him not to give up, since they are still alive. Marin, Shaina, Jabu and the others give him words of encouragement, and as Seiya yells out her name, Seika recovers her memory, screaming out her brother's name. Seiya recovers, burning his Cosmos, and amazingly, his Cloth transforms and covers him, revealing a new Pegasus Cloth. Hypnos appears, revealing it is a God Cloth, an armor capable of rivaling the armors worn by the Olympian Gods. Seiya recovers Athena's Cloth, taken by Thanatos, but as he attacks, Seiya blocks the technique and counters with Meteor of Pegasus, destroying Thanatos' Cloth. Thanatos attacks again, but is finally killed by the Pegasus Comet Punch. Seiya heads for Hades' Tower to save Saori.

Hypnos stands in Seiya's way, but is unable to stop him and Seiya continues towards the tower. Ikki fights Hypnos but is tossed aside. Shun stops Hypnos with his Nebula Chain, as it changes into the Andromeda God Cloth covering his body. Ikki takes the chance to go and help Seiya. Hypnos uses Eternal Drowsiness to lull Shun into a deep sleep. Before Hypnos can kill Shun, Hyoga and Shiryu also awaken their Cygnus and Dragon God Cloth. Seiya finally arrives at Hades' Temple and finds Saori, with the urn almost completely red. Seiya tries attacking the urn, but Hades' soul appears, telling him to give up and that his attacks will come back to him if he launches them. Hypnos tries to make Hyoga and Shiryu fall asleep, but they avoid it, and team up to destroy the God of Sleep, allowing Shun to wake up. Ikki arrives to help Seiya, but after he is attacked, he is exposed to Athena's blood, which awakens the Phoenix God Cloth. Both Saints attack the urn, but are unable to break it. Ikki notices Hades' soul surrounding the Tower, deducing that Hades' body is located there. As Hypnos dies, he warns the Saints to stop Hades from entering his body, otherwise the world will come to ruin. Before Seiya and Ikki reach the body, it's too late. Hades' soul enters his own body, and the God of the Underworld resurrects, setting his sights on Athena, trapped in the urn. After easily repelling Seiya and Ikki's charge, Hades then unsheathes his sword.