Bryan Mills fights for his life inside a secret Mexican prison and plans a series of dangerous deals to put him on track for escape to the United States. But plans change when Mills and a young migrant girl are taken by human traffickers. Meanwhile, Christina Hart leverages her spycraft skills to obtain powerful new software that could locate Mills, and enlists two unlikely allies to aid in her mission to bring Mills home.

Hart takes a solo mission to track down the mentor who betrayed her, and the team tries to locate her before it's too late.