Bryan Mills fights for his life inside a secret Mexican prison and plans a series of dangerous deals to put him on track for escape to the United States. But plans change when Mills and a young migrant girl are taken by human traffickers. Meanwhile, Christina Hart leverages her spycraft skills to obtain powerful new software that could locate Mills, and enlists two unlikely allies to aid in her mission to bring Mills home.

A laid-off worker kidnaps a high-powered accountant in revenge for his lost pension, and the team gets swept up in a case of class warfare when Bryan decides to help the kidnapper get justice.

When the President's emergency "football" is stolen, Bryan and the team must recover it before classified national security measures fall into dangerous hands.

Bryan and Santana must extract a nuclear physicist long thought dead, from a secret North Korean prison compound. Meanwhile, Kilroy faces a moral dilemma when Hart asks him to locate a criminal wanted by a foreign government.

Hart takes a solo mission to track down the mentor who betrayed her, and the team tries to locate her before it's too late.

Bryan must stop an act of biological terrorism when invasive species are stolen from the Global Seed Bank in Norway.

The daughter of a government official working overseas is taken, and an unexpected suspect derails Bryan's rescue operation.