In the summer of 1985, a Delta 191 aircraft was diverted away from a thunderstorm, only to be struck by powerful winds and plummet to the ground. Flames engulfed the front of the plane and more than 130 people died in a tragic accident that would eventually expose, and eliminate, an invisible killer.

Rescuers have to look to the past to solve the riddle of Flight 611, a China Airlines 747 that disappeared 20 minutes after taking off.

On 22 August 1985, an engine of British Airtours Flight 28M fails during takeoff, puncturing a hole in the wing fuel tank and starting a fire. The crew successfully abandons the takeoff and stops the aircraft on the runway, but the fire spreads to the cabin. 55 people die before they can evacuate, mainly due to inhaling toxic smoke. The investigation found that fatigue of a part in the engine caused it to fail.

On 16 August 1987, Northwest Airlines Flight 255 stalls as it lifts off from Detroit Metropolitan Airport and crashes just beyond the runway, killing 154 of the 155 people on board and two people on the ground. The investigation showed that the pilots failed to configure the aircraft's flaps and slats for takeoff.

On 25 February 2009, Turkish Airlines Flight 1951 is on approach to land at Schiphol in Amsterdam, when it stalls and crashes 1.5 kilometres from the runway. Nine people, including the three cockpit crew members, are killed. A faulty radar altimeter caused the aircraft's flight control computer to automatically reduce engine thrust prematurely, and the flight crew failed to notice the resulting drop in airspeed until it was too late.

On 26 May 1991, the thrust reverser of the first engine of Lauda Air Flight 004 accidentally deploys in mid-flight causing the plane to spiral out of control and disintegrate about 100 miles northwest of Bangkok. All of the 223 passengers and crew die in the crash.

On 18 September 1961, a Douglas DC-6 operated by Transair Sweden, carrying Dag Hammarskjöld, the second Secretary-General of the United Nations, crashes en route to cease-fire negotiations in Northern Rhodesia during the Congo Crisis. All of the 16 passengers and crew members are killed.

On 27 March 1977, the deadliest-ever aviation accident occurs at Los Rodeos Airport (now known as Tenerife-North Airport) in the Canary Islands. KLM Flight 4805 and Pan Am Flight 1736 collide on the runway in thick fog during the KLM aircraft's attempt to take off, killing 583 people.

On 26 September 1997, Garuda Indonesia Flight 152 crashes into mountainous woodlands while trying to land at Polonia International Airport in Medan, North Sumatra, in low visibility. All 234 people on board are killed.

On 15 November 1987, Continental Airlines Flight 1713 stalls and crashes off the right side of the runway shortly after taking off in a snowstorm from Stapleton International Airport in Denver, Colorado, on a scheduled flight to Boise, Idaho, killing 28 of the 82 people on board.

(West Air Sweden Flight 294) A cargo jet plummets to earth in the Swedish Arctic. And as investigators pore over the evidence, a terrifying picture of chaos and confusion emerges.

On 29 October 2018, Lion Air Flight 610 enters a nosedive and crashes into the Java Sea shortly after taking off from Soekarno–Hatta International Airport in Jakarta, Indonesia, on a flight to Pangkal Pinang.

On 9 June 1995, Ansett New Zealand Flight 703 suffers a landing gear malfunction during final approach to Palmerston North Airport in New Zealand. The aircraft descends until it crashes into hilly terrain as the pilots try to resolve the problem. 4 of the 21 people on board are killed.

When a two-billion-dollar B-2 Stealth Bomber named the Spirit of Kansas crashes in Guam, it’s up to the US Air Force to investigate the most expensive aviation accident of all time.

When basketball legend Kobe Bryant is killed in a helicopter crash in Los Angeles, investigators look for clues amid a global outpouring of grief.