A satirical inversion of the ideal of the perfect American nuclear family, they are an eccentric wealthy family who delight in everything grotesque and macabre, and are never really aware that people find them bizarre or frightening. In fact, they themselves are often terrified by "normal" people.
In his quest for a bride to break his immortal curse, a 939-year-old guardian of souls meets a grim reaper and a sprightly student with a tragic past.
The charming and still-single Joey, who has struck out on his own and moved to Hollywood, hoping to truly make it as an actor. After reuniting with his high-strung sister Gina, Joey moves in with Michael, his 20-year-old genius nephew, who unbelievably is literally a rocket scientist. However, what Joey lacks in book smarts he makes up for with people smarts – making him the best new friend his nephew could ask for.
Widower and professor Porter Waide has his life turned upside down with the arrival of his football player brother, Bobby, who's gotten into so much trouble that he's been contracted to live with a responsible relative. This move also disrupts the lives of Porter's impressionable son, Oscar, and Bobby's perpetually annoyed agent, Dena.
Luo Fei Fei, a girl from the 21st century, was transported to a mysterious world of the past -Huang Dao Guo. In the nation of Huang Dao, its leadership is rotated among the 12 constellation owners every thousand years. There, Fei Fei meets the current emperor of the nation, Bei Tang Yi, who is also the owner of the Capricorn constellation.
Andy is a dissolute out-of work musician who forges an unlikely alliance with his 12-year-old nephew Errol after being morally blackmailed into looking after him by his chaotic sister Sam - all on the day Andy was planning to kill himself. Not a natural with either kids or responsibility, he tries to keep his new charge out of trouble while being knee-deep in it himself.
Wu Yi is a little boy who has lost his parents but lives a warm and happy life with his aunt, Wu Jiao Jiao, who runs a martial arts hall. His uncle, domineering president Qi Mo, wants his father to meet his only grandson and so he begins a custody battle with Wu Jiao Jiao, who is a passionate young woman that will not give up easily.
Joon Hyeok is an unpopular musician whose life has hit rock bottom. He had already broken off his relationship with his older sister, Joon Hee, when her son appeared before him. His nephew developed Obsessive–compulsive disorder after his mother divorced his stepfather. Joon Hyeok takes his nephew in and looks after him. Joon Hee divorced her physically abusive husband after 12 years of marriage. She moved into an inexpensive apartment and now faces losing custody of her son to her ex-husband and his mother.
The series follows Vinnie Bassett, proprietor of a pop culture memorabilia store who only takes breaks to read comic books and play video games. His bachelor life comes to a halt when he assumes guardianship of his incredibly intelligent and mature nephew, Wendell. They soon find that 12-year-old Wendell may be just the parent Vinnie needs.