A stagecoach is attacked by a group of outlaws who make off with a pile of money. Unfortunately for Mexican Juan, the sheriff believes he's one of the criminals and has him locked up. But the beautiful Cheel thinks Juan is innocent, and offers to help him escape. Overhearing their plan, the real mastermind behind the heist forces Juan to act as the runner for the money.

In dem Western Arizona-Express gerät der Mexikaner Juan (Anthony George) in den Verdacht, ein Postkutschenräuber zu sein. Selbst seine Freundin Cheel (Vera Ralston) verliert ihr Vertrauen in ihn, als er mit den Banditen augenscheinlich gemeinsame Sache macht.