That's My Line was a summer CBS reality show developed by Mark Goodson, one of the creators of What's My Line?. The show highlights the unusual occupations of ordinary people, but unlike What's My Line?, it has no panel or game components; the show is rather along the same lines as NBC's Real People and ABC's That's Incredible!.

It was hosted by Bob Barker and announced by Johnny Olson, both associated with Goodson-Todman's hit game show, The Price Is Right. The series was co-hosted by Suzanne Childs and Tiiu Leek, and joined during the 1981 run by Kerry Millerick. The thrust of the show during the 1981 season also changed from unusual occupations to an emphasis on the funny, bizarre, or ridiculous.

Notable moments included voice artist Mel Blanc having a contest with an audience member on who does voice acting the best and magician James Randi contesting James Hydrick's psychic abilities.