Dom is killed in a helicopter accident that also severely injures String. Dom's niece, Jo, inherits and takes charge of Santini Air. The Company sends Locke to regain possession of Airwolf, he recruits Major Mike Rivers ,an Air Force pilot to help him find and fly the craft. Together they rescue St. John from a jungle prison and he and Jo round out the new Airwolf team.

St. John is following Jo in a bi-plane as she tries out a new navigation device in a helicopter over an area of wilderness, when her helicopter is suddenly struck from the ground by a laser-beam that sends her chopper crashing down. St. John's plane is also hit, but he manages to land in the nearby town of Santa Mira before he looses consciousness. Waking up the next day in the local hospital, he is infuriated that nobody seems to believe his story and is out looking for Jo. But when he arrives at the crash-site, there is no sign of the crash ever happened, and as St. John tries to find out what is going on, he finds that the small boom town is held in some kind of grip of fear...

A former female employee of the Company, who has suffered mental trauma after a Company mission went wrong, insists that she is seeing strange lights and hearing unexplained noises in the middle of the night, over her remote home and the nearby Indian burial ground in the rural town of Devil's Ridge. Jason sends St. John and Mike to investigate, and they are just as sceptical as everyone else, putting it down to her mental troubles, but the source of the disturbances is actually a stolen super-helicopter – a third version of Airwolf called ""The Scorpion"" – is hidden in the area, waiting to be picked up by KGB agents...

St. John and crew are under a deadline to recover a piece of stolen satellite hardware which is needed for an upcoming space shuttle flight.

The grandfather of one of four juvenile delinquents Jo and Mike have taken camping plans on killing the rest of the camping party in order to regain custody of his grandson.

Locke does not get along with the Russian agent he has been assigned to work with to guard a train full of nerve gas that is to be destroyed.

St. John and Locke uncover a military cover-up when they represent opposite sides at a court martial.

The Russians reluctantly agree to allow the Airwolf team help them contain a nuclear power plant that has had a meltdown.

The Russians reluctantly agree to allow the Airwolf team help them contain a nuclear power plant that has had a meltdown.

The Airwolf team is assigned to guard the daughter of an Interpol agent who is marked for death by terrorists.

The Airwolf team tracks down the source of a genetically engineered virus that has claimed the life of one of St. John's friends.

A security leak is blamed on Locke when his behavior changes as a result of seeing a friend killed on a mission behind the Iron Curtain.

A Japanese Kamikaze pilot who survived being shot down by St. John's father during WWII plans on restoring his honor by killing St. John and destroying a nuclear power plant.

A jet manufacturer sabotages his own plane that St. John is test piloting rather than let St. John reveal its inferior construction.

The Airwolf team is sent in to stop a group that has taken control of ten Soviet and ten American nuclear missile silos and threatens to set them off unless everyone agrees to total nuclear disarmament.

Mike and the wife of an East German double agent! pilot he had been impersonating are kidnapped at an air show in Paris.

A banana republic dictator takes St. John and the family of one of St. John's friends- who had discovered that the dictator was skimming American aid- hostage on a remote island.

Jo is lured to Afghanistan by an old boyfriend who has sold her as a bride to a rebel leader.

Locke's girlfriend is given a behavior implant module which forces her to turn Locke over to a lady scientist who uses the same procedure on Locke in order to gain control of Airwolf.

The Airwolf team is sent to stop a man who has hijacked a Japanese freighter carrying nuclear waste. The man plans to blackmail the nations of the Earth into guaranteeing all diseased persons.

The Airwolf team travels around the world as they put an opium ring run by St. John's former commander out of business.

Jo's ailing father aids the Airwolf team in recovering radioactive material stolen by a group of Neo-Nazi 5.

John comes to the aid of an old flame whose husband was killed by drug dealers.