A voodoo priestess animates her dead son to take revenge on the gangsters that killed him.

A series of suicides among high-society matrons coincides with a bizarre jewel theft by a towering Indian who mysteriously disappears when cornered. Kolchak investigates and finds that the Indian is a ""diablero,"" a cursed cliff-dwelling Indian medicine man condemned to walk the earth gathering an eternal horde of jewels. The diablero can change shape into the form of a coyote or crow, and hypnotize anyone with its eyes. Carl must seek the diablero in the highest place he can find, and turn the power of its eyes against it.

Several Indian construction workers are killed during high-rise work on a new hospital. They leave the job, and the hospital is completed. However, a series of strange electrocutions continue to plague the hospital after its grand opening. Kolchak investigates and finds that a ""bear-god"" spirit, Matchemonedo, was resurrected from its burial spot beneath Lake Michigan by the hospital construction. Now the creature, which feeds on energy, is beginning to awaken. Kolchak must convince the hospital officials to re-refrigerate the ""bear-god"" and drive it back into hibernation before it awakens once and for all.