Travel to 1920s Tennessee as the Carter Family, Jimmie Rodgers, and the Memphis Jug Band make their first records with producer Ralph Peer on a revolutionary portable recording machine, creating the first recordings of R&B and country songs.

Travel to the rural South as Elder Burch, Charley Patton and others record early Delta blues, gospel and protest songs. The Great Flood of 1927 devastates Mississippi River communities, leading to northern migration and Chicago Blues by Howlin' Wolf.