A young woman named Dorothy Gale dreams of becoming a singer but is unable to pursue her dreams. After being swept up by a tornado with her pet prawn Toto, Dorothy embarks on a journey to meet the Wizard of Oz, the person who both Dorothy and the citizens of Oz believe can help make her dream come true.

Thirty years ago, aliens arrive on Earth. Not to conquer or give aid, but to find refuge from their dying planet. Separated from humans in a South African area called District 9, the aliens are managed by Multi-National United, which is unconcerned with the aliens' welfare but will do anything to master their advanced technology. When a company field agent contracts a mysterious virus that begins to alter his DNA, there is only one place he can hide: District 9.