Based on Hashim Nadeem’s novel of the same name, the titular protagonist is born in unfortunate circumstances – a poor family of eleven people and dark skin. In a society obsessed with fair skin, he finds himself in start contrast with his name (lit. fairy's child)

“IS” stands for “intersexual,” a term referring to people who cannot clearly be classified as male or female, and who may biologically possess characteristics of both sexes. Rokuhana's manga primarily deals with the troubles faced by the young Hoshino Haru (played by Fukuda), an intersexual who was registered as a girl at birth but has been raised as a boy.

Goriki plays Aihara Miwako, a mysterious classmate who tries to get close to Haru. Inoue Masahiro has been cast as Ibuki Kenji, a member of the soccer club whom Haru begins having feelings for. Nishida Naomi and Minami Kaho play Miwako's and Haru's mothers, respectively.

Every human being in this world is God's creation. Indeed God loves all its being equally, yet we humans tend to create the boundaries of gender.