A newly married couple, in the process of starting a family, learn many of life's important lessons from their trouble-loving retriever, Marley. Packed with plenty of laughs to lighten the load, the film explores the highs and lows of marriage, maturity and confronting one's own mortality, as seen through the lens of family life with a dog.

Scott Turner has 3 days left in the local police department before he moves to a bigger city to get some 'real' cases—not just misdemeanors. When Amos Reed is murdered, Scott sets himself on the case, but the closest thing to a witness to the murder is Reed's dog, Hooch, which Scott has to take care of—to avoid Hooch being 'put to sleep'.