The wife of an elite government official left her husband, and a young journalist is sent to investigate the case. But his boss has a hidden agenda.

Akira's wife walks out on him, leaving him to confide in his gangster brother-in-law. Using only a cryptic note as a clue the two brothers go on a road trip to find his wife. After a series of violent encounters with strangers, Akira meets a prostitute. The pair start a relationship. After Akira finds his wife, he questions whether he still wants to be with her.

Ægteparret Dean og Cindy er kommet til det punkt, hvor familielivet er blevet en stadig kamp. Henover en weekend flygter de fra hverdagen for at forsøge at redde ægteskabet. I bagspejlet kan de se hvad der engang fik dem til at blive lidenskabeligt forelskede og det der gjorde at ingen forhindringer var uoverstielige. Filmen blev nomineret til en Oscar-statuette i 2011, men vandt den desværre ikke.