Office temp Charlotte Cantilini thinks she's found Mr. Right when she starts dating gorgeous surgeon Dr. Kevin Fields. But there's a problem standing in the way of everlasting bliss: Kevin's overbearing and controlling mother, Viola. Fearing she'll lose her son's affections forever, Viola decides to break up the happy couple by becoming the world's worst mother-in-law.

When Tess Kelley realizes her daughter Jenny Kelley still isn't over her divorce from musician Rick Meadows, the irresponsible, ever-absent father of her little boy Jesse, and thus fails to make progress with friend and promising potential fiance Miles Healey, she places an ad on her daughter's behalf on a lonely hearts internet website. She then starts an anonymous relationship through the dating service with charming British-born literature professor Peter Campbell, who lives in America. Then Peter comes to meet Jenny in person, but who will end up with whom or stay alone?