A gang of bandits takes control of Tucson in preparation for the arrival of a consignment of gold, with only a band of voluntary soldiers trying to outwit them and save the town.
Hoot Gibson and Bob Stanley ride into Arizona seeking the killer of Bob's father, who managed the stagecoach line in Eggleston for Kelso McGuire.
The Governor of Kansas hires six gunfighters to overthrow the tyrannical rule of the self-appointed sheriff of Abilene.
Stage line owner Brent has his men robbing Halliday stages and when his manager Waring learns of it, Brent has him killed. Jeff Waring arrives and takes his uncle's job. He soon learns what's happening and the Durango Kid goes into action. This keeps Halliday going and gives them a chance to get the mail contract by winning the stagecoach race.
Gallant Cisco "kidnaps" murder suspect Ellen from the authorities, then sets about to prove her innocence, all with the cooperation of a sympathetic sheriff.
As prisoner Ed Archer is being transferred, the stage is attacked and crashes. Archer escapes the attackers but Ranger Rocky Lane catches up with him. As Rocky is bringing him in, Archer is attacked again. Somebody wants Archer killed and Rocky, now suspecting Archer is innocent, decides to find out who and why.
The Hartley--Goodrich stage line suffers a double blow when its founders, Frank Hartley and Marcus Goodrich, are killed during robbery attempts. Goodrich's daughter Judith and the company foreman, Gabby Hayes, are determined to keep the business going, despite debt caused by the string of attacks.
A gang of outlaws gather at a desert saloon after robbing a bank. However, the loot is missing and paranoia sets in, as the outlaws start knocking each other off
Lash and Fuzzy sent to help John Watson with his stage line arrive to find him murdered. Recognizing the outlaws they trail them to their leader Baxter. But before Baxter can tell who the big boss is he is shot. After getting the stage through to assure the mail contract, Lash now realizes who the boss is.
Saved from a lynching party by a pair of young women, an itinerant cowpuncher signs on as a stagecoach guard to protect a shipment of gold.
Storm is out to wreck Ace's stage line. When Tex arrives to help Ace, Storm brings in hired killer Mule Bates. But Tex and Bates know each other and the two devise a plan to fool Storm.
A former outlaw eludes the authorities by masquerading as a cowboy.
A band of outlaws, led by "Papa" Clellan, hold up in a ghost town as they plan an attack on a wagon train loaded with gold. The unexpected arrival of a stagecoach forces the gang to hold the passengers and driver as hostages. The later arrival of a wanderer, John Trey, sets in motion events not in "Papa" Clellan's original plan.
Dave Saunders and his sidekick Chito, cowhands looking for work, arrive in Sundown Valley, Wyoming just in time to stop sheep ranch foreman Jess Rawlins from lynching cattleman Tug Caldwell. Rawlins seems set on starting a range war; but why? Before Dave and Chito can find out, they must convince Chris Marvin, Rawlins's attractive boss, that he's no good...and get out from under a framed murder charge. - Rod Crawford
In order to obtain a stage coach mail contract, a new road must be built. A gang of outlaws try to prevent the building of the road.
Fuzzy's niece is killed in a stagecoach hold-up. Billy and Fuzzy quickly learn that the culprit, who not only killed all the passengers but also absconded with $40,000, may be holed up in lawless Pecos City.
Rocky Lane, Special Investigator for Wells Fargo, shows up just in time to save the stage from being robbed. Unable to find the mastermind, or even the outlaws who rob the stage, Rocky goes undercover as an outlaw.
Bandit Cheyenne Harry reforms because of the faith placed in him by Molly Young and her father. Soon, however, Harry is lured from the straight and narrow when he meets his old friend Ben Kent and consents to participate in Kent's plan of robbing a stagecoach.
The coming of the railroad to Cedar City spells the end of the stagecoach as the government gives the mail contract to the fastest means of delivery. McCord loses the stagecoach line gambling with the new buyer, but has enough hidden money to buy a ranch and some cattle. To make more money, he starts a gang to rob the railroad, express offices and steal cattle. But the railroads send out special agent Cameron to end his reign of violence.
When Decker's gang holds up a stage, henchman Lefty takes a lady's rings. Later lefty accidentally exposes the rings buying ammunition and Cheyenne sees them. When Lefty tries to shoot Cheyenne he is captured. Now Cheyenne wants the rest of the gang and their leader.