Famosos científicos de todo el mundo están desapareciendo misteriosamente, y la reportera del Chronicle, Polly Perkins y el hábil aviador Sky Captain lo están investigando. Arriesgando sus vidas viajan a lugares exóticos, pero, ¿podrá este dúo detener al Dr. Totenkopf, el malvado personaje que está detrás de este plan para destruir la tierra? Ayudados por Franky Cook, comandante de un escuadrón femenino, y un genio de la tecnología llamado Dex, Polly y Sky Captain parecen ser la única esperanza del planeta.

In the near future Nassim, terrorist leader, storms computer company headquarters. His aim is deadly computer virus that could bring him world domination. Nick, company janitor and ex-cop, will get in his way.

The USA is attacked by a large group of well organized terrorists who communicate through a computer network via satellite. A bunch of highschool kids has hacked the password and gained access. Believing it's a game they unknowingly cause terror acts all over the country. An anti-terror force fights against the terrorists.