Şebnem Hassanisoughi was born in Istanbul. Her father is of Azerbaijani descent from Iran. Her mother is Turkish.

Sebnem took on roles in some very significant shows such as, 'Firar', 'Kayip Sehir', 'Tatar Ramazan', 'Bana Artik Hicran De', 'Poyraz Karayel', and 'Vatanim Sensin'. She recently took a place in various digital series, such as 'Andropause', 'Hot Skull' for Netflix, 'Metot' for Gain and 'Star' for Disney+, which will be launched soon.

Her role in the 2011 movie 'Geriye Kalan', shot by Cigdem Vitrinel brought her two very important awards. Hassanisoughi was awarded 'Best Actress' at the 12th Izmir International Film Festival, and received the 'Ayhan Isik Special Award' at the 18th Sadri Alisik Actor's Awards. After working with Alphan Eseli on his film 'Eve Dönüs Sarikamis 1915' in 2012, she appeared in Zeki Demirkubuz's film 'Bulanti', and with her performance in this movie, won 'Best Supporting Actress' at the 48th Siyad Awards. Later, Hassanisoughi took on the role of 'Sara' in Tayfur Aydin's 2016 movie 'Siyah Karga'. She was also honored with the 20th Year Special Award at the 20th Flying Broom International Women's Film Festival. Following, Sebnem participated in the movie 'Butterflies', which got Grand Jury Prize at Sundance 2018. In the same year, she appeared in the Danish movie 'Lifeboat' with Sofia Helin and Pal Sverre Hagen.