Inspector Lunge investigates the murder of a prostitute and suspects a senator named Dr. Boltzmann of involvement. His dedication to his work however takes a toll on his family life.

Meanwhile, the vindictive Eva continues to press Lunge to catch Tenma. She also has a new lover, her garderner.

Karl Neumann and Lotte Frank are both students who read latin to Hans Georg Schubert. Lotte attempts to assist Karl in finding out his past while trying to figure out the identity of a boy who reads to Schubert on Thursdays. When they both discover who he is, they find the boy, Edmund Farren, in his dormitory, dead.

Lotte, Frank and Karl are drifting apart. Lotte meets Nina Fortner and they become friends. Dr. Tenma searches for a perfect spot to shoot Johan.

Dr. Tenma has a gun pointed at Roberto, but Roberto has the rifle pointed at him. Nina, Dr.Reichwen and Dieter arrive to find the whole library in flames. People are trapped inside and the doors are all locked. Karl reads the report on his mother's life and death. Dr. Tenma tries to rescue those trapped in the building. Johan reveals the monster inside of him to Schuwald.

Schubert, with the help of Reichwein, re-explores his past with Karl Neumann's real mother and realizes his link to Johan. As news of Tenma's arrest spreads, various people react with shock and horror, with the exception of Eva Heinemann, who is insistent that Tenma pay dearly for rejecting her. Suk tries to leave the hospital he is in to try to help Tenma, but is stopped by the Prague Police who inform him that Grimmer has sent a note to them exonerating Suk from any involvement of the deaths of the police officers. Runge also gets news of the arrest as well, but he is more interested in the Mansion of Red Roses, where he obtains a letter possibly addressed to the twins' mother. Tenma is deported back to Dusseldorf.

Dr. Tenma takes Verderman hostage in a desperate search for Eva. And Verderman's dark past is revealed.

Tenma manages to find Martin. A drunken Eva spots Johan at a party. Martin receives his final orders from his boss but his feelings gets in the way. And Martin gets way over his head when he tries to investigate Johan and his disciple, and the truth about his past is revealed.

Nina confronts Johan who presents her with a story on what happened when many people were poisoned at the Mansion of Red Roses. Nina realizes that she was the one who witnessed these deaths, the shock of this revelation nearly drives her to suicide, but she is saved by Tenma. Capek is gunned down by members of his organization when they find out about the guard that Capek killed.